Inflammation as a universal pathogenetic link between injury, repair and regeneration, in acute coronary syndrome. From experiment to clinic
https://doi.org/10.18087/cardio.2668
Abstract
Theory of atherogenesis and its complications underwent numerous changes. Today we observe that inflammation is a universal pathogenetic link between various processes such as atherosclerosis, rupture of atherosclerotic plaques and following myocardial infarction, post-infarction cardiac repair and heart failure. This review discusses examples, difficulties, and prospects of implementation of anti-inflammatory therapies in management of acute coronary syndrome and its complications.
About the Authors
V. V. Ryabov
Tomsk National Research Medical Center of the Russian Academy of Science, Cardiology Research Institute
Russian Federation
Russian Federation
Kievskaya 111a, Tomsk 634012
A. E. Gombozhapova
Tomsk National Research Medical Center of the Russian Academy of Science, Cardiology Research Institute
Russian Federation
Russian Federation
Kievskaya 111a, Tomsk 634012
Yu. V. Rogovskaya
Tomsk National Research Medical Center of the Russian Academy of Science, Cardiology Research Institute
Russian Federation
Russian Federation
Kievskaya 111a, Tomsk 634012
M. S. Rebenkova
Tomsk National Research Medical Center of the Russian Academy of Science, Cardiology Research Institute
Russian Federation
Russian Federation
Kievskaya 111a, Tomsk 634012
Yu. V. Alekseeva
Tomsk National Research Medical Center of the Russian Academy of Science, Cardiology Research Institute
Russian Federation
Russian Federation
Kievskaya 111a, Tomsk 634012
Yu. G. Kzhyshkowska
National Research Tomsk State University
Russian Federation
Russian Federation
Lenin Avenue 36, Tomsk, 634050
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Review
For citations:
Ryabov V.V., Gombozhapova A.E., Rogovskaya Yu.V., Rebenkova M.S., Alekseeva Yu.V., Kzhyshkowska Yu.G. Inflammation as a universal pathogenetic link between injury, repair and regeneration, in acute coronary syndrome. From experiment to clinic. Kardiologiia. 2019;59(8S):15-23. (In Russ.) https://doi.org/10.18087/cardio.2668
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