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Early Myocardial Calcification on the Background of Fulminant Lymphocytic-Macrophage Myocarditis
https://doi.org/10.18087/cardio.2025.8.n2920
Abstract
Fulminant myocarditis is characterized by an extremely severe course and remains a life-threatening disease. Only isolated cases of diffuse myocardial calcification in myocarditis have been reported. For this reason, the process of natural evolution of myocardial structural changes and their impact on the cardiovascular system have not yet been sufficiently studied. A clinical case of a 37-year-old patient with morphologically proven fulminant lymphocytic myocarditis and extensive myocardial calcification was selected for the analysis. This article analyzes the course of the disease, an algorithm for diagnosis and selection of a treatment method, and provides a review of previously published studies.
Supporting agencies: The study was performed as part of the State Assignment of the Ministry of Health of the Russian Federation “Study of the pathogenesis of myocarditis and pericarditis from the standpoint of autoinflammation and autoimmunity” # 25 25 00337. Conflict of interest All authors declare no potential conflict of interest that would require disclosure in the present article.
About the Authors
S. V. Mayrina
Almazov National Medical Research Center, St. Petersburg
Russian Federation
Russian Federation
Junior Researcher at the National Research Institute of Connective Tissue Dysplasia
I. A. Makarov
Almazov National Medical Research Center, St. Petersburg
Russian Federation
pathologist of the pathological anatomy department of the University Clinic and assistant of the department of pathological anatomy with the clinic, Ph.D.in Medicine
Russian Federation
pathologist of the pathological anatomy department of the University Clinic and assistant of the department of pathological anatomy with the clinic, Ph.D.in Medicine
K. B. Lapshin
Almazov National Medical Research Center, St. Petersburg
Russian Federation
Russian Federation
Head, Intensive Care Unit Department
D. V. Alekseeva
Almazov National Medical Research Center, St. Petersburg
Russian Federation
Assistant Professor of the Department of Radiology and Medical Imaging with Clinic, Ph.D.in Medicine
Russian Federation
Assistant Professor of the Department of Radiology and Medical Imaging with Clinic, Ph.D.in Medicine
A. P. Semyonov
Almazov National Medical Research Center, St. Petersburg
Russian Federation
Russian Federation
Head of the Department
O. M. Moiseeva
Almazov National Medical Research Center, St. Petersburg
Russian Federation
Russian Federation
Director of the Heart and Vascular Institute, Head and Chief Researcher of the Department of Non-Coronarogenic Heart Diseases, Doctor of Medical Sciences, Professor, Honored Scientist of St. Petersburg
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Review
For citations:
Mayrina S.V., Makarov I.A., Lapshin K.B., Alekseeva D.V., Semyonov A.P., Moiseeva O.M. Early Myocardial Calcification on the Background of Fulminant Lymphocytic-Macrophage Myocarditis. Kardiologiia. 2025;65(8):89-95. (In Russ.) https://doi.org/10.18087/cardio.2025.8.n2920
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