Взаимосвязь между глобальной функцией левого желудочка, определяемой индексом Tei, и долгосрочной выживаемостью у пациентов с неишемической дилатационной кардиомиопатией

Цель. Идиопатическая дилатационная кардиомиопатия (ДКМП) является одной из ведущих причин сердечной недостаточности (СН) с низкой фракцией выброса (ФВ). Индекс Tei является надежным маркером, отражающим как систолическую, так и диастолическую функцию левого желудочка (ЛЖ), и имеет прогностическое значение у пациентов с ДКМП. Мы стремились исследовать взаимосвязь между индексом Tei и долгосрочной выживаемостью у пациентов с ДКМП.
Материал и методы. В исследование включено 98 пациентов с неишемической ДКМП. Среднее время выживания больных составило 59 мес.
Результаты. Индекс Tei был значительно выше у умерших пациентов (0,64±0,08 против 0,71±0,12 соответственно; p=0,01). Конечный систолический объем ЛЖ и фракция выброса ЛЖ (ФВ ЛЖ) были независимыми прогностическими факторами и предсказывали ухудшение долгосрочной выживаемости. Кроме того, пациенты с ФВ ЛЖ ≥32,7% и индексом Tei ≤0,76 имели значительно большее время выживания.
Заключение. Настоящее исследование показало, что индекс Tei достоверно связан со смертностью, а пациенты как с низкой ФВ ЛЖ (≤32,7%), так и с высокими значениями индекса Tei (≥0,76) имели более короткую ожидаемую продолжительность жизни. Исходя из результатов исследования, мы предполагаем, что индекс Tei может быть полезным эхокардиографическим маркером для прогнозирования долгосрочной выживаемости у пациентов с ДКМП.

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