The Relationship Between Atrial Fibrillation and Parathyroid Hormone in Heart Failure Outpatients
https://doi.org/10.18087/cardio.2023.9.n2277
Abstract
Background Atrial fibrillation (AF) is a common arrhythmia in heart failure (HF). Plasma concentrations of parathyroid hormone (PTH) have been shown to increase in HF. The relationship between PTH concentrations and the presence of AF in HF is, however, unknown. This study analyzed the relationship between plasma PHT concentrations and AF in patients with systolic HF.
Material and methods 131 consecutive, stable HF patients, who were admitted to the HF outpatient clinic, were included in this prospective, observational study. Patients were classified as those with AF (n = 36) and those in sinus rhythm (SR, n = 95).
Results PTH concentrations were markedly higher in patients with AF compared to the patients in SR [85 (15-320) vs. 112 (30-326) U / ml, p=0.007]. PTH, creatinine clearance, hemoglobin, creatinine, age, and left ventricular ejection fraction were found to be related to AF by univariate analysis; though, multivariate logistic regression analysis showed that only PTH concentration was independently related to AF.
Conclusion PTH concentrations can be used to indicate AF in patients with systolic HF.
Supporting agencies: No conflict of interest is reported.
About the Authors
Kerkutluoglu Murat
Kahramanmaras Sutcu Imam University
Turkey
Turkey
Assist. Prof
Faculty of Medicine, Department of Cardiology Kahramanmaras, Turkey
Yucel Oguzhan
Near East University
Turkey
Turkey
Assist. Prof
Faculty of Medicine, Department of Cardiology, Nicosia, Turkish Republic of Northern Cyprus
Gunes Hakan
Kahramanmaras Sutcu Imam University
Turkey
Turkey
Assoc Prof.
Faculty of Medicine, Department of Cardiology Kahramanmaras, Turkey
Ozgul Ufuk
Aydın Atatürk State Hospital
Turkey
Turkey
MD
Department of Cardiology, Aydin Turkey
Yilmaz Mehmet Birhan
Dokuz Eylül University
Turkey
Turkey
Prof.
Faculty of Medicine, Department of Cardiology, İzmir, Turkey
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Review
For citations:
Murat K., Oguzhan Yu., Hakan G., Ufuk O., Birhan Y.M. The Relationship Between Atrial Fibrillation and Parathyroid Hormone in Heart Failure Outpatients. Kardiologiia. 2023;63(9):51-55. https://doi.org/10.18087/cardio.2023.9.n2277
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