Cognitive Disorders and Dementia in Old Patients With Arterial Hypertension

The article describes the definition of dementia, its diagnostic criteria, classification. Differences in the pathogenesis and clinical manifestations of different types of dementia are considered. The issues of interrelation of arterial hypertension and the risk of development of cognitive disorders and dementia in old and very old people are discussed in detail. Data on the effect of antihypertensive drugs of different groups on the risk of dementia and the state of cognitive functions are presented. The evidence base of dihydropyridine calcium antagonist amlodipine and thiazide-like diuretic indapamide-retard is discussed with respect to the prevention of dementia and cognitive decline and their beneficial effect on cognitive function in patients with arterial hypertension.

артериальная гипертония, когнитивные нарушения, деменция, пожилой возраст, антигипертензивная терапия, амлодипин, индапамид ретард, фиксированные комбинации антигипертензивных препаратов, arterial hypertension, cognitive disorders, dementia, old age, antihypertensive therapy, amlodipine, indapamide, fixed combinations of antihypertensive drugs

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