Impact of Arterial Hypertension on the Formation of the Risk of Mortality. Results of a 27-Year Prospective Study
https://doi.org/10.18087/cardio.2018.9.10168
Abstract
Objective: to investigate the impact ofarterial hypertension (AH) on formation ofthe risk oftotal and cardiovascular mortality. Materials and methods. The 27-year cohort prospective study was conducted on the sample of unorganised population of Tomsk (n=1 546, age 20-59 years, 630 men, 916 women). At the first stage (1988-1991) we studied the prevalence of AH, at the second stage (2015) we investigated overall and cardiovascular mortality and the prognostic significance of AH in shaping mortality. Criterion of AH was blood pressure (BP) ≥140/90 mm Hg or (in persons with BP <140/90 mm Hg) treatment with antihypertensive drugs or discontinuation of this treatment less than 2 weeks before initial examination. Results. The study demonstrated significant contribution ofAH to the formation of the risk of mortality: among individuals with AH relative risk (RR) of all-cause death was 2.2 and that of cardiovascular death - 3.38. An AH related elevation of mortality risk was observed both among women and men and in all age groups. We also observed direct correlation between mean BP values and total and cardiovascular mortality rates. Conclusion. A clear contribution of AH in the formation of the risk of mortality was revealed. Cardiovascular diseases were main cause of death in individuals with AH. In men the risk of cardiovascular mortality was higher, but predictive value of AH was worse in women.
About the Authors
Alena Yu. Ivanova
Siberian State Medical University
Russian Federation
Russian Federation
I. V. Dolgalev
Siberian State Medical University
Russian Federation
Russian Federation
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Review
For citations:
Ivanova A.Yu., Dolgalev I.V. Impact of Arterial Hypertension on the Formation of the Risk of Mortality. Results of a 27-Year Prospective Study. Kardiologiia. 2018;58(9):5-11. (In Russ.) https://doi.org/10.18087/cardio.2018.9.10168
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