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Capecitabine and vasospastic angina: a clinical case

https://doi.org/10.18087/cardio.2022.2.n1708

Abstract

The article presents a clinical case of a 78-year-old female patient with a clinical picture of vasospastic angina during the capecitabin treatment. The issues under discussion include difficulties of diagnosing vasospastic angina, a potential danger and incidence of coronary vasospastic reactions during chemotherapy with drugs of this group, and current approaches to prevention and correction of fluoropyrimidine cardiotoxicity. The presented clinical case confirms that vasospasm is a manifestation of capecitabin cardiotoxicity. This case also illustrates the importance of interaction and co-ordination of the work of oncologists and cardiologists at all stages of care of oncological patients. 

 

About the Authors

I.  P. Kolos
Medical Center of the Federal Property Management Agency, Moscow, Russia
Russian Federation


V. A. Chernyshova  
N.I. Pirogov Municipal Clinical Hospital #1, Moscow, Russia
Russian Federation


E.  V. Konstantinova
N.I. Pirogov Municipal Clinical Hospital #1, Moscow, Russia "Pirogov Russian National Research Medical University", Moscow, Russia
Russian Federation


M.  Yu. Gilyarov
N.I. Pirogov Municipal Clinical Hospital #1, Moscow, Russia "Pirogov Russian National Research Medical University", Moscow, Russia
Russian Federation


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Review

For citations:


Kolos I.P., Chernyshova   V.A., Konstantinova E.V., Gilyarov M.Yu. Capecitabine and vasospastic angina: a clinical case. Kardiologiia. 2022;62(2):36-41. (In Russ.) https://doi.org/10.18087/cardio.2022.2.n1708

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ISSN 0022-9040 (Print)
ISSN 2412-5660 (Online)