Взгляд на гипертрофию миокарда с позиции транскриптомики и метаболомики

В обзоре представлены основные направления в изучении гипертрофии миокарда с позиции транскриптомики и метаболомики. Понимание механизмов, запускающих гипертрофию миокарда, позволит перейти от фундаментальных исследований к персонифицированному клиническому применению инновационных технологий в лечении заболеваний сердца, таких как таргетная терапия. В настоящее время разработаны определенные методы диагностики и прогнозирования сердечно-сосудистых заболеваний, основанные на метаболомном профилировании и оценке экспрессии микроРНК. Прогресс в области изучения молекулярных и генетических процессов, лежащих в основе развития сердечно-сосудистых заболеваний, может дать неоценимо важную информацию для клинической кардиологии.

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