Prognostic value of epicardial fat thickness in coronary heart disease patients after myocardial revascularization
https://doi.org/10.18087/cardio.2020.3.n874
Abstract
Objective To study the role of epicardial adipose tissue (EAT) in determination of risk for adverse course of ischemic heart disease (IHD) in patients after myocardial revascularization.
Materials and Methods This study included 217 subjects, 182 IHD patients and 35 evaluated individuals without IHD. Percutaneous coronary intervention (PCI) was performed for 104 patients and coronary bypass (CB) was performed for 78 patients. Also echocardiography (EchoCG) and cardiac computed tomography were performed.
Results In IHD patients, EAT volume and thickness were greater than in evaluated subjects without IHD. The composite endpoint (CEP) was observed after PCI more frequently than after CB. In IHD patients with an EAT thickness of 8.5 to 10.2 mm measured with EchoCG in the atrioventricular groove, the risk of CEP was 4.3 times higher after myocardial revascularization than with thicker or thinner EAT regardless of the revascularization method.
Conclusion An EAT thickness of 8.5 to 10.2 mm in the atrioventricular groove as measured with EchoCG was associated with a risk of adverse IHD course in patients who have underwent myocardial revascularization.
Keywords
Supporting agencies: The authors declare no conflict of interest.
About the Authors
E. A. Polyakova
Federal State Budgetary Education Institution “Pavlov First Saint-Petersburg State Medical University”
Federal Almazov North-West Medical Research Centre
Russian Federation
PhD, MD, assistant of the Department of Therapy of the Faculty with a course of endocrinology, cardiology and functional diagnostics, Researcher at the Laboratory of Arterial Hypertension, Scientific Research Institute of Cardiovascular Diseases Federal State Budgetary Education Institution, “Pavlov First Saint-Petersburg State Medical University”.Senior Researcher, Research Laboratory of Metabolic Syndrome, Federal Almazov North-West Medical Research Centre
Russian Federation
PhD, MD, assistant of the Department of Therapy of the Faculty with a course of endocrinology, cardiology and functional diagnostics, Researcher at the Laboratory of Arterial Hypertension, Scientific Research Institute of Cardiovascular Diseases Federal State Budgetary Education Institution, “Pavlov First Saint-Petersburg State Medical University”.Senior Researcher, Research Laboratory of Metabolic Syndrome, Federal Almazov North-West Medical Research Centre
O. A. Berkovich
Federal State Budgetary Education Institution “Pavlov First Saint-Petersburg State Medical University”
Russian Federation
PhD, MD, professor of the Department of Therapy of the Faculty with a course of endocrinology, cardiology and functional diagnostics, “Pavlov First Saint-Petersburg State Medical University”.
Russian Federation
PhD, MD, professor of the Department of Therapy of the Faculty with a course of endocrinology, cardiology and functional diagnostics, “Pavlov First Saint-Petersburg State Medical University”.
E. I. Baranova
Federal Almazov North-West Medical Research Centre
Russian Federation
Head of Research Laboratory of Metabolic Syndrome, Federal Almazov North-West Medical Research Centre
Russian Federation
Head of Research Laboratory of Metabolic Syndrome, Federal Almazov North-West Medical Research Centre
Review
For citations:
Polyakova E.A., Berkovich O.A., Baranova E.I. Prognostic value of epicardial fat thickness in coronary heart disease patients after myocardial revascularization. Kardiologiia. 2020;60(3):4-13. https://doi.org/10.18087/cardio.2020.3.n874
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