Консенсус экспертов Российского кардиологического общества, Общества специалистов по сердечной недостаточности, Ассоциации онкологов России и Ассоциации кардиоонкологов Евразии «Кардиопротекция 2025: современные подходы к профилактике кардиоваскулотоксичности противоопухолевой терапии». Часть II. Первичная профилактика кардиоваскулотоксичности: стратегия защиты миокарда и сосудов

Цель – представить согласованные экспертами рекомендации по первичной профилактике кардиоваскулотоксичности противоопухолевой терапии в рамках Консенсуса Российского кардиологического общества, Общества специалистов по сердечной недостаточности, Ассоциации онкологов России и Ассоциации кардиоонкологов Евразии «Кардиопротекция 2025». Вторая часть Консенсуса фокусируется на стратегии защиты миокарда и сосудов до начала или на ранних этапах противоопухолевого лечения. В документе рассмотрены основные принципы первичной профилактики кардиоваскулотоксичности: междисциплинарное взаимодействие кардиологов и онкологов на этапе планирования лечения, возможности управления модифицируемыми факторами риска, методы фармакологической кардиопротекции, подходы к превентивному скринингу (включая клиническую оценку, биомаркеры и методы визуализации), нефармакологические меры профилактики (физическая активность, коррекция нутритивного статуса, искусственный интеллект и цифровое управление мониторинга); особенности профилактики при применении ключевых противоопухолевых групп препаратов (антрациклины, HER2-таргетные средства, ингибиторы тирозинкиназ, анти-VEGF агенты, ингибиторы иммунных контрольных точек). Документ призван оптимизировать ведение пациентов для снижения риска развития сердечно-сосудистых осложнений на фоне противоопухолевой терапии.

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