ВАЖНО! Правила приравнивания журналов, входящих в международные базы данных к журналам перечня ВАК.
Ответ на официальный запрос в ВАК журнала Кардиология.

Preview

Kardiologiia

Advanced search

The clinical features of heart failure in elderly and old age

https://doi.org/10.18087/cardio.2487

Abstract

The aim of the study. To evaluate the prevalence and clinico-functional features of myocardial dysfunction in persons 65 years or older in the primary care setting. Materials and methods. The prospective cohort study “Crystal” included participants 65 years and older. The arm of “Crystal” study evaluated a random sample size of 284 people. All participants were performed echocardiography using portable digital ultrasound scanner Mindray M5 ultrasound transducer of 2.5-3.5 MHz. It was also evaluated the clinical manifestations of heart failure (HF) on the scale SHOCKS, medical history and anthropometric data and parameters of the geriatric examination. Were determined muscle strength, walking speed, emotional status (Geriatric Depression Scale) and cognitive status (MiniMental State Examination). Assessment of dependence on external assistance was carried out based on the Barthel Index (Barthel Index). Results. The prevalence of all forms of myocardial dysfunction was 80.3%, among them of 73.2% of participants had clinical manifestations of heart failure, which was not associated with type or severity of structural and functional abnormalities of the myocardium. Symptoms and signs of HF were characterized by low sensitivity for detection in older people with MD and may be associated with other conditions. The most common complaint was shortness of breath (59%), with high sensitivity for the diagnosis (89%) but low specificity (51%). Patients with clinical manifestations of HF are more likely to have a BMI of over 30 kg/m2, cognitive disorders, suspected depression, lower walking speed and low grip strength by dynamometry. In addition, participants with symptoms were older age (75,3±5.6 years vs 72,7±5.5 years, p<0.001). The analysis showed a significant negative effect of MD on survival of participants in the study: overall risk of mortality in participants with myocardial dysfunction aged 65-74 years was higher than 4.8, and at age 75 and over 2.9 times. The conclusion Low diagnostic value of symptoms of heart failure in the population older people were demonstrated. The need for a full geriatric examination at the outpatient stage in combination with early holding of echocardiography to persons with suspected myocardial dysfunction of the myocardium was showed, in connection with negative prognostic impact.

About the Author

E. V. Frolova
I.I. Mechnikov North-West State Medical University
Russian Federation


References

1. Mosterd A, Hoes AW. Clinical epidemiology of heart failure. Heart. 2007;93 (9):1137-46. DOI:10.1136/hrt. 2003.025270

2. Morgan S, Smith H, Simpson I, Liddiard GS, Raphael H, Pickering RM et al. Prevalence and clinical characteristics ofleft ventricular dysfunction among elderly patients in general practice setting: cross sectional survey. BMJ. 1999;318 (7180):368-72. PMID:9933201

3. Forman DE, Arena R, Boxer R, Dolansky MA, EngJJ, FlegJL et al. Prioritizing Functional Capacity as a Principal End Point for Therapies Oriented to Older Adults With Cardiovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association. Circulation. 2017;135 (I6):e894-918. DOI:10.1161/CIR. 0000000000000483

4. Doherty TJ. Ue influence of aging and sex on skeletal muscle mass and strength. Curr Opin Clin Nutr Metab Care. 2001;4 (6):503-8. PMID:11706284

5. Nessler J, Skrzypek A. Chronic heart failure in the elderly: a current medical problem. Pol Arch Med Wewn. 2008;118 (10):572-80. PMID:19112819

6. Remes J, Miettinen H, Reunanen A, Pyörälä K. Validity of clinical diagnosis of heart failure in primary health care. Eur Heart J. 1991;12 (3):315-21. PMID:2040313

7. Hawkins NM, Petrie MC, Jhund PS, Chalmers GW, Dunn FG, McMurrayJJV. Heart failure and chronic obstructive pulmonary disease: diagnostic pitfalls and epidemiology. European Journal of Heart Failure. 2009; 11 (2):130-9. DOI:10.1093/eurjhf/hfn013

8. Gurina NA, Frolova EV, Degryse JM. A Roadmap of Aging in Russia: Ue Prevalence of Frailty in Community-Dwelling Older Adults in the St. Petersburg District-Ue «Crystal» Study: A Roadmap ofAging in Russia. Journal of the American Geriatrics Society. 2011;59 (6):980 8. DOI:10.1111/j. 1532-5415.2011.03448. x

9. Мареев В. Ю., Фомин И. В., Агеев Ф. Т., Беграмбекова Ю. Л., Васюк Ю. А., Гарганеева А. А. и др. Клинические рекомендации ОССН - РКО - РНМОТ. Сердечная недостаточность: хроническая (ХСН) и острая декомпенсированная (ОДСН). Диагностика, профилактика и лечение. Кардиология. 2018; 58 (S6):8-164. DOI:10.18087/cardio. 2475

10. Lang RM, Bierig M., Devereux RB, Flachskampf FA, Foster E., Pellikka PA et al. Recommendations for Chamber Quantification: A Report from the American Society of Echocardiography»s Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in Conjunction with the European Association of Echocardiography, a Branch of the European Society of Cardiology. Journal of the American Society of Echocardiography. 2005;18 (12):1440-63. DOI:10.1016/j. echo. 2005.10.005

11. Khouri SJ, Maly GT, Suh DD, Walsh T.E. A practical approach to the echocardiographic evaluation of diastolic function. Journal of the American Society of Echocardiography. 2004; 17 (3):290-7. DOI:10.1016/j. echo. 2003.08.012

12. Paulus WJ, Tschöpe C., Sanderson JE, Rusconi C., Flachskampf FA, Rademakers FE et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. European Heart Journal. 2007;28 (20):2539-50. DOI:10.1093/eurheartj/ehm037

13. Рекомендации по лечению А.Г. ESH/ ESC 2013. Российский Кардиологический Журнал. 2014; (1 (105)): 7-94.

14. Turusheva A., Frolova E., Degryse J-M. Age-related normative values for handgrip strength and grip strength»s usefulness as a predictor of mortality and both cognitive and physical decline in older adults in northwest Russia. J. Musculoskelet Neuronal Interact. 2017;17 (1):417-32. PMID:28250246

15. Studenski S. Gait Speed and Survival in Older Adults.JAMA. 2011;305 (1):50. DOI:10.1001/jama. 2010.1923

16. Yesavage JA, Brink TL, Rose TL, Lum O., Huang V., Adey M. et al. Development and validation of a geriatric depression screening scale: a preliminary report. J. Psychiatr Res. 1982; 17 (1):37-49. PMID ;7183759

17. de Craen AJM, Heeren TJ, Gussekloo J. Accuracy of the 15-item geriatric depression scale (GDS-15) in a community sample of the oldest old. International Journal of Geriatric Psychiatry. 2003;18 (1):63-6. DOI:10.1002/gps. 773

18. Folstein MF, Folstein SE, McHugh P.R. «Mini-mental state». A practical method for grading the cognitive state ofpatients for the clinician. J. Psychiatr Res. 1975;12 (3):189-98. PMID:1202204

19. Mahoney FI, Barthel DW. Functional evaluation: Ue Barthel index. Md State Med J. 1965;14:61-5. PMID:14258950

20. Fonseca C. Diagnosis of heart failure in primary care. Heart Failure Reviews. 2006;11 (2):95-107. DOI:10.1007/s10741-006-9481-0

21. Vais B., Rizzoug N., Pasquit A., Wallimacq P., Van Pottilbirgh G., Mathe C. et al. Ui prevalence of cardiac dysfunction and the correlation with poor functioning among the very elderly. International Journal of Cardiology. 2012;155 (1):134-43. DOI:10.1016/j. ijcard. 2011.07.024

22. Cesari M., Kritchevsky SB, Penninx BWHJ, Nicklas BJ, Simonsick EM, Newman AB et al. Prognostic Value of Usual Gait Speed in Well-Functioning Older People - Results from the Health, Aging and Body Composition Study: Usual gait speed in older persons. Journal of the American Geriatrics Society. 2005;53 (10):1675-80. DOI:10.1111 /j. 1532-5415.2005.53501. x

23. Vaes B., de Ruijter W., Gussekloo J., Degryse J. Ue accuracy of plasma natriuretic peptide levels for diagnosis of cardiac dysfunction and chronicheart failure in community-dwelling elderly: a systematic review. Age and Ageing. 2009;38 (6):655-62. DOI:10.1093/ageing/afp157

24. Pavasini R., Guralnik J., Brown JC, di Bari M., Cesari M., Landi F. et al. Short Physical Performance Battery and all-cause mortality: systematic review and meta-analysis. BMC Medicine [Internet]. 2016 [cited 2018]; 14 (1). DOI:10.1186/s12916-016-0763-7

25. Tribouilloy C., Rusinaru D., Mahjoub H., Souliere V., Levy F., Peltier M. et al. Prognosis of heart failure with preserved ejection fraction: a 5 year prospective population-based study. European Heart Journal. 2008;29 (3):339-47. DOI:10.1093/eurheartj/ehm554

26. Iolascon G., Di Pietro G., Gimigliano F., Mauro GL, Moritti A., Giamattii MT it al. Physical exercise and sarcopinia in older people: position paper of the Italian Society of Orthopaedics and Medicine (OrtoMid). Clin Cases Miner Bone Metab. 2014;11(3):215-21. PMID:25568656


Review

For citations:


Frolova E.V. The clinical features of heart failure in elderly and old age. Kardiologiia. 2018;58(8S):4-11. (In Russ.) https://doi.org/10.18087/cardio.2487

Views: 1037


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0022-9040 (Print)
ISSN 2412-5660 (Online)