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Pharmacotherapy of heart failure with reduced ejection fraction: heart failure basic therapy and an episode of decompensation

https://doi.org/10.18087/cardio.2023.3.n2418

Abstract

A qualitative change in the risk profile after an episode of decompensated heart failure (HF) calls for an as immediate as possible therapeutic response. In the absence of uniform guidelines for the sequence and timing of administering the background therapy during the hospitalization period and the subsequent “vulnerable” period, clinicians have to rely on available expert opinions and results of conducted studies. The article focuses on an evidence base for the use of background therapy for HF during the above-mentioned periods. Special attention is paid to the conditions and principles of initiating this therapy.

About the Authors

Zh. D. Kobalava
Russian University of Peoples’ Friendship
Russian Federation

Corresponding Member of the Russian Academy of Sciences, Professor, Doctor of Medical Sciences, Head of the Department of Internal Diseases with a course of cardiology and functional diagnostics named after V.S. Moiseev, Medical Institute, Peoples' Friendship University of Russia

Moscow, Russia

 



I. S. Nazarov
Russian University of Peoples’ Friendship
Russian Federation

postgraduate student of the Department of Internal Diseases with a course of cardiology and functional diagnostics named after V.S. Moiseev, Medical Institute, Peoples' Friendship University of Russia. 

Moscow, Russia



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Kobalava Zh.D., Nazarov I.S. Pharmacotherapy of heart failure with reduced ejection fraction: heart failure basic therapy and an episode of decompensation. Kardiologiia. 2023;63(3):66-76. (In Russ.) https://doi.org/10.18087/cardio.2023.3.n2418

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