Effect of the Prognostic Nutrition Index on Long-Term Outcomes in Unprotected Left Main Coronary Artery Revascularization
Tuncay Güzel,
Eyüp Avcı,
Tuncay Kırış,
Baran Arık,
Bayram Arslan,
Kamran İldırımlı,
Bünyamin Yıldırım,
Lokman Argun,
Muhammed Demir,
Adem Aktan,
Mehmet Özbek,
Burhan Aslan,
Mesut Gitmez,
Mehmet Karaçalılar,
Çayan Çakır,
Raif Kılıç,
Faruk Ertaş https://doi.org/10.18087/cardio.2023.11.n2367
Abstract
Objective The prognostic nutritional index (PNI) is a practical, applicable, prognostic scoring system. However, its clinical significance in unprotected left main coronary artery (ULMCA) patients undergoing percutaneous coronary intervention (PCI) has not yet been clarified. This study aimed to examine the relationship between malnutrition as assessed by PNI and major adverse cardiac events (MACE) in ULMCA patients undergoing PCI.
Material and methods 185 patients who were hospitalized in our clinic underwent coronary angiography, had a critical LMCA lesion, and underwent angiography-guided PCI were included. The study population was divided into tertiles based on the PNI values. A high PNI (n=142) was defined as a value in the third tertile (≥ 34.0), and a low PNI (n=43) was defined as a value in the lower 2 tertiles (< 34.0). The primary endpoint was MACE.
Results MACE and mortality rates in the low PNI group were significantly higher compared to the high PNI group (51 % vs. 30 %, p=0.009; 44 % vs. 20 %, p=0.002, respectively). High PNI (HR:1.902; 95 % CI:1.112-3.254; p=0.019), previous stroke (HR:3.025; 95 % CI:1.038-8.810; p=0.042) and SYNTAX score (HR:1.028; 95 % CI:1.004-1.057, p=0.023) were independent predictors of MACE in the multivariable cox regression analyzes.
Conclusions In patients undergoing ULMCA PCI, nutritional status can be considered an indicator of MACE rates by evaluating the PNI score. This index can be used for risk classification.
Supporting agencies: No conflict of interest is reported.
About the Authors
Tuncay Güzel
Health Science University, Gazi Yasargil Training and Research Hospital
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Eyüp Avcı
Medical School, Balikesir University
Turkey
Turkey
MD
Department of Cardiology, Balikesir, Turkey
Tuncay Kırış
Ataturk Training and Research Hospital, Izmir Katip Celebi University
Turkey
Turkey
MD
Department of Cardiology, Izmir, Turkey
Baran Arık
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Bayram Arslan
Ergani State Hospital
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Kamran İldırımlı
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Bünyamin Yıldırım
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Lokman Argun
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Muhammed Demir
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Adem Aktan
Mardin Training and Research Hospital
Turkey
Turkey
MD
Department of Cardiology, Mardin, Turkey
Mehmet Özbek
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Burhan Aslan
Health Science University, Gazi Yasargil Training and Research Hospital
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Mesut Gitmez
Batman Training and Research Hospital
Turkey
Turkey
MD
Department of Cardiology, Batman, Turkey
Mehmet Karaçalılar
Dicle University Faculty of Medicine
Turkey
Turkey
Department of Cardiovascular Surgery, Diyarbakir, Turkey
Çayan Çakır
Bismil State Hospital
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Raif Kılıç
Diyarlife Hospital
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
Faruk Ertaş
Dicle University Faculty of Medicine
Turkey
Turkey
MD
Department of Cardiology, Diyarbakir, Turkey
References
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Review
For citations:
Güzel T., Avcı E., Kırış T., Arık B., Arslan B., İldırımlı K., Yıldırım B., Argun L., Demir M., Aktan A., Özbek M., Aslan B., Gitmez M., Karaçalılar M., Çakır Ç., Kılıç R., Ertaş F. Effect of the Prognostic Nutrition Index on Long-Term Outcomes in Unprotected Left Main Coronary Artery Revascularization. Kardiologiia. 2023;63(11):73-79. https://doi.org/10.18087/cardio.2023.11.n2367
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