Рossibility of using European (HFA-PEFF) and American (H2FPEF) algorithms for diagnosing heart failure with preserved ejection fraction in Russian clinical practice
https://doi.org/10.18087/cardio.2022.12.n2280
Abstract
This article focuses on the significance of a unified approach to diagnosing heart failure with preserved left ventricular ejection fraction (HFpEF). The key hemodynamic index of HFpEF is increased left ventricular filling pressure (LVFP) and its noninvasive marker, the E / e’ value obtained by tissue Doppler echocardiography (EchoCG). The modern verified algorithms for HFpEF diagnosis, HFA–PEFF and Н2FPEF, mandatorily take into account the E / e’ value. However, the routing use of these algorithms in the Russian practice may be complicated since even among “advanced” specialists who are interested in heart failure, 38% of the interviewed do not use or do not know how to use tissue Doppler EchoCG or the algorithm for diagnosing HFpEF with E / e’. In addition to the obvious way of overcoming this problem by equipping respective medical facilities with ultrasonic apparatuses with tissue Doppler EchoCG software and educating physicians, a possibility of using simplified HFA algorithm without the E / e’ value is being considered. However, such approach will inevitably lead to erroneous estimation of the probability of HFpEF and, at the best, to underestimation of this probability with ensuing mistakes in diagnosis and treatment. Simplifying the HFA–PEFF and H2FPEF algorithms by omitting one or more parameters is possible but this requires a special investigation to develop a new rating scale and actually a new algorithm, which, in turn, will require a new validation.
About the Authors
F. T. AgeevRussian Federation
M.D., Prof. , Chief Researcher
Moscow, Russia
E. B. Yarovaya
Russian Federation
Consultative and diagnostic department, MD, PhD
Moscow, Russia
A. G. Ovchinnikov
Russian Federation
Leading Researcher
Moscow, Russia
References
1. Vaduganathan M, Michel A, Hall K, Mulligan C, Nodari S, Shah SJ et al. Spectrum of epidemiological and clinical findings in patients with heart failure with preserved ejection fraction stratified by study design: a systematic review. European Journal of Heart Failure. 2016;18(1):54–65. DOI: 10.1002/ejhf.442
2. Oshchepkova E.V., Lazareva N.V., Satlykova D.F., Tereshchenko S.N. The first results of the Russian register of chronic heart failure. Kardiologiia. 2015;55(5):22–8.
3. Pitt B, Pfeffer MA, Assmann SF, Boineau R, Anand IS, Claggett B et al. Spironolactone for Heart Failure with Preserved Ejection Fraction. New England Journal of Medicine. 2014;370(15):1383–92. DOI: 10.1056/NEJMoa1313731
4. Ageev F.T., Ovchinnikov A.G. Treatment of patients with heart failure and preserved ejection fraction: reliance on clinical phenotypes. Kardiologiia. 2022;62(7):1–10. DOI: 10.18087/cardio.2022.7.n2058
5. Zile MR, Baicu CF, Gaasch WH. Diastolic Heart Failure – Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle. New England Journal of Medicine. 2004;350(19):1953–9. DOI: 10.1056/NEJMoa032566
6. Maron BA, Cockrill BA, Waxman AB, Systrom DM. The Invasive Cardiopulmonary Exercise Test. Circulation. 2013;127(10):1157–64. DOI: 10.1161/CIRCULATIONAHA.112.104463
7. Ovchinnikov A.G., Ageev F.T., Alekhin M.N., Belenkov Yu.N., Vasyuk Yu.A., Galyavich A.S. et al. The role of diastolic transthoracic stress echocardiography with incremental workload in the evaluation of heart failure with preserved ejection fraction: indications, methodology, interpretation. Kardiologiia. 2020;60(12):48–63. DOI: 10.18087/cardio.2020.12.n1219
8. Paulus WJ, Tschope C, Sanderson JE, Rusconi C, Flachskampf FA, Rademakers FE et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. European Heart Journal. 2007;28(20):2539–50. DOI: 10.1093/eurheartj/ehm037
9. Pieske B, Tschope C, de Boer RA, Fraser AG, Anker SD, Donal E et al. How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European Heart Journal. 2019;40(40):3297– 317. DOI: 10.1093/eurheartj/ehz641
10. Guazzi M, Wilhelm M, Halle M, Van Craenenbroeck E, Kemps H, de Boer RA et al. Exercise testing in heart failure with preserved ejection fraction: an appraisal through diagnosis, pathophysiology and therapy – A clinical consensus statement of the Heart Failure Association and European Association of Preventive Cardiology of the European Society of Cardiology. European Journal of Heart Failure. 2022;24(8):1327–45. DOI: 10.1002/ejhf.2601
11. Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Circulation. 2018;138(9):861–70. DOI: 10.1161/CIRCULATIONAHA.118.034646
12. Parcha V, Malla G, Kalra R, Patel N, Sanders-van Wijk S, Pandey A et al. Diagnostic and prognostic implications of heart failure with preserved ejection fraction scoring systems. ESC Heart Failure. 2021;8(3):2089–102. DOI: 10.1002/ehf2.13288
13. Reddy YNV, Kaye DM, Handoko ML, van de Bovenkamp AA, Tedford RJ, Keck C et al. Diagnosis of Heart Failure With Preserved Ejection Fraction Among Patients With Unexplained Dyspnea. JAMA Cardiology. 2022;7(9):891. DOI: 10.1001/jamacardio.2022.1916
Review
For citations:
Ageev F.T., Yarovaya E.B., Ovchinnikov A.G. Рossibility of using European (HFA-PEFF) and American (H2FPEF) algorithms for diagnosing heart failure with preserved ejection fraction in Russian clinical practice. Kardiologiia. 2022;62(12):4-10. https://doi.org/10.18087/cardio.2022.12.n2280