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Randomized Controlled Trials in Patients With Heart Failure in Russia Following the Study TOPCAT: What Awaits us in the Future

https://doi.org/10.18087/cardio.2017.10025

About the Author

Yuri M. Lopatin
Volgograd State Medical University; Volgograd Regional Clinical Cardiology Centre
Russian Federation


References

1. Pitt B., Pfeffer M. A., Assmann S. F., Boineau R., Anand I. S., Claggett B. et al. Spironolactone for heart failure with preserved ejection fraction. N Engl J Med. 2014;370(l5):1383-92. doi:10.1056/NEJMoa1313731

2. Pfeffer M. A., Claggett B., Assmann S. F., Boineau R., Anand I. S., Clausell N. et al. Regional variation in patients and outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT ) trial. Circulation. 2015;131(1): 34-42. doi:10.1161/CIRCULATI0NAHA.114.013255

3. Bristow M. R., Enciso J. S., Gersh B.J., Grady C., Rice M. M., Singh S. et al. Detection and management of geographic disparities in the TOPCAT trial: lessons learned and derivative recommendations. JACC Basic Transl Sci. 2016;1(3):180-9. doi:10.1016/ j.jacbts. 2016.03.001

4. de Denus S., O'Meara E., Desai A.S., Claggett B., Lewis E.F., Leclair G. et al. Spironolactone metabolites in TOPCAT - new insights into regional variation. N EnglJ Med. 2017;376 (17):1690 2. doi:10. 1056/NEJMc1612601

5. Ferreira J.P., Girerd N., Rossignol P., Zannad F. Geographic differences in heart failure trials. Eur J Heart Fail. 2015;17(9):893-905. doi:10.1002/ejhf.326.

6. Ponikowski P., Voors A.A., Anker S.D., Bueno H., Cleland J.G.F., Coats A.J.S. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur J Heart Fail. 2016 Aug;18(8):891-975. doi: 10.1002/ejhf.592.

7. Mareev V. Yu., Fomin I. V., Ageev F. T., Arutyunov G. P., Begrambekova Yu. L., Belenkov Yu. N. et al. Clinical guidelines. Chronic heart failure (CHF). Russian Heart Failure Journal. 2017;18 (1):3-40 DOI: 10.18087/rhfj.2017.1.2346.


Review

For citations:


Lopatin Yu.M. Randomized Controlled Trials in Patients With Heart Failure in Russia Following the Study TOPCAT: What Awaits us in the Future. Kardiologiia. 2017;57(8):47-50. (In Russ.) https://doi.org/10.18087/cardio.2017.10025

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ISSN 0022-9040 (Print)
ISSN 2412-5660 (Online)