Clinical case: early connection of valsartan/sacubitril in the treatment of hypertension
https://doi.org/10.18087/cardio.2022.5.n1977
Abstract
Metabolic syndrome is a disease the World Health Organization has called a new pandemic of the 21st century. Arterial hypertension is one of the criteria for this diagnosis and a determinant of damage to major target organs. The present clinical case demonstrates an experience of treatment of arterial hypertension associated with metabolic syndrome with a valsartan/sacubitril molecular complex.
About the Authors
N. G. LozhkinaRussian Federation
Doctor of Medical Sciences, professor
Novosibirsk, Russia
A. N. Spiridonov
Russian Federation
ordinator
Novosibirsk, Russia
References
1. Pucci G, Alcidi R, Tap L, Battista F, Mattace-Raso F, Schillaci G. Sexand gender-related prevalence, cardiovascular risk and therapeutic approach in metabolic syndrome: A review of the literature. Pharmacological Research. 2017;120:34–42. DOI: 10.1016/j.phrs.2017.03.008
2. Uryasev O.M., Gorbunova D.Yu., Sherbakova O.N., Pyko A.A. Metabolic syndrome as an unsolved problem of medicine and modern society. Vestnik of the Smolensk State Medical Akademy. 2017;16(1):160–4.
3. Schmieder RE, Wagner F, Mayr M, Delles C, Ott C, Keicher C et al. The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study. European Heart Journal. 2017;38(44):3308–17. DOI: 10.1093/eurheartj/ehx525
4. Wehland M, Simonsen U, Buus NH, Krüger M, Grimm D. An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension. Expert Opinion on Pharmacotherapy. 2020;21(10):1133–43. DOI: 10.1080/14656566.2020.1735356
5. Rørth R, Jhund PS, Yilmaz MB, Kristensen SL, Welsh P, Desai AS et al. Comparison of BNP and NT-proBNP in Patients with Heart Failure and Reduced Ejection Fraction. Circulation: Heart Failure. 2020;13(2):e006541. DOI: 10.1161/CIRCHEARTFAILURE.119.006541
6. Lozhkina N.G., Mukaramov I., Stafeeva E.A., Tolmacheva A.A., Parkhomenko O.M. Choice of optimal basic therapy in patients with chronic heart failure after decompensation episode. Medical & pharmaceutical journal ‘Pulse’. 2020;22(7):60–7. DOI: 10.26787/nydha-2686-6838-2020-22-7-60-67
7. Balmforth C, Simpson J, Shen L, Jhund PS, Lefkowitz M, Rizkala AR et al. Outcomes and Effect of Treatment According to Etiology in HFrEF: An Analysis of PARADIGM-HF. JACC: Heart Failure. 2019;7(6):457–65. DOI: 10.1016/j.jchf.2019.02.015
8. Hanssen H, Boardman H, Deiseroth A, Moholdt T, Simonenko M, Kränkel N et al. Personalized exercise prescription in the prevention and treatment of arterial hypertension: a Consensus Document from the European Association of Preventive Cardiology (EAPC) and the ESC Council on Hypertension. European Journal of Preventive Cardiology. 2022;29(1):205–15. DOI: 10.1093/eurjpc/zwaa141
9. Kobalava Zh.D., Konradi A.O., Nedogoda S.V., Shlyakhto E.V., Arutyunov G.P., Baranova E.I. et al. Arterial hypertension in adults. Clinical guidelines 2020. Russian Journal of Cardiology. 2020;25(3):149–218. DOI: 10.15829/1560-4071-2020-3-3786
Review
For citations:
Lozhkina N.G., Spiridonov A.N. Clinical case: early connection of valsartan/sacubitril in the treatment of hypertension. Kardiologiia. 2022;62(5):72-74. (In Russ.) https://doi.org/10.18087/cardio.2022.5.n1977