A case of arrhythmogenic right ventricular cardiomyopathy associated with myocardial inflammation
https://doi.org/10.18087/cardio.2023.1.n1768
Abstract
Recent years have been marked by a number of published reports that have shown a high frequency of signs of myocardial inflammation in patients with confirmed arrhythmogenic right ventricular cardiomyopathy (ARVC). This article presents a clinical case of typical phenotypic manifestations of ARVC associated with morphometric signs of subacute myocarditis. A 66-year-old man presented to the emergency department with signs of arrhythmogenic shock caused by ventricular tachycardia. Examination detected electrocardiographic signs of (ARVC), visualized signs of right ventricular dilatation, increased trabeculation, and wall fibrosis. Endomyocardial biopsy of the right ventricular wall showed degenerative alterations of cardiomyocytes with perivascular lymphocytic infiltration and areas of granulation tissue. New facts that evidence inflammatory alterations of the myocardium will still require specifying and reconsidering positions of expert consensuses on diagnostics and treatment of ARVC.
Keywords
Arrhythmogenic right ventricular cardiomyopathy,
inflammation,
myocarditis,
Epsilon wave,
right ventricular dysfunction
Supporting agencies: No conflict of interest is reported.
About the Authors
A. L. Bobrov
Pavlov First St. Petersburg State Medical University
Russian Federation
Russian Federation
Professor of the Department of Functional Diagnostics
Saint Petersburg, Russia
A. N. Kulikov
Pavlov First St. Petersburg State Medical University
Russian Federation
Russian Federation
Head of the Department of Functional Diagnostics
Saint Petersburg, Russia
V. A. Dvinyanidov
European Institute for Family Health
Russian Federation
Russian Federation
Chief physician
Saint Petersburg, Russia
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Review
For citations:
Bobrov A.L., Kulikov A.N., Dvinyanidov V.A. A case of arrhythmogenic right ventricular cardiomyopathy associated with myocardial inflammation. Kardiologiia. 2023;63(1):68-72. (In Russ.) https://doi.org/10.18087/cardio.2023.1.n1768
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