Expert consensus regarding treatment of iron deficiency in stable and decompensated patients with heart failure
https://doi.org/10.18087/cardio.2021.4.n1639
Abstract
In recent years there has been significant interest in treating iron deficiency (ID) in patients with heart failure (HF) due to its high prevalence and detrimental effects in this population. As stated in the 2020 Russain HF guidelines, Intravenous ferric carboxymaltose remains the only proven therapy for ID.
This document was prompted by the results from the recent AFFIRM-AHF trial which demonstrates that treatment of ID after acute HF decompensation reduces the risk of future decompensations.
Experts have concluded that in HF patients with acute decompensation, a left ventricular ejection fraction of < 50% and ID, Intravenous ferric carboxymaltose reduces future HF hospitalisations. Patients with stable HF may also benefit from treatment of ID to improve quality of life and alleviate symptoms. It is, therefore, reasonable to screen for and treat ID in patients with HF.
About the Authors
Yu. V. MareevRussian Federation
Senior Researcher
S. R. Gilarevsky
Russian Federation
Professor of the Department of Clinical Pharmacology and Therapy
Yu. L. Begrambekova
Russian Federation
Leading Researcher Medical Research and Education Center of Moscow State University M.V. Lomonosova
Yu. M. Lopatin
Russian Federation
Head of the Department of Cardiology, Cardiovascular and Thoracic Surgery
A. A. Garganeeva
Russian Federation
Head of the Department of General Clinical Cardiology and Epidemiology of Cardiovascular Diseases
D. V. Duplyakov
Russian Federation
Deputy Chief Physician for Medical Affair
Zh. D. Kobalava
Russian Federation
Head of the Department of Internal Medicine and Clinical Pharmacology, Faculty of Advanced Training of Medical Workers
E. Z. Golukhova
Russian Federation
Academic of the Russian Academy of Sciences, Ph.D. Med., Professor, Acting Head of A.N. Bakulev National Medical Scientific Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation
N. A. Koziolova
Russian Federation
Head of the Department of Propedeutics of Internal Diseases No. 2
А. V. Panov
Russian Federation
Head of the Research Department of Ischemic Heart Disease,
Т. А. Lelyavina
Russian Federation
Leading Researcher, Laboratory of High-Tech Methods for the Treatment of Heart Failure
O. M. Drapkina
Russian Federation
Director
V. Yu. Mareev
Russian Federation
Chief Researcher Medical Research and Education Center of Moscow State University M.V. Lomonosova, Moscow, Russia
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Review
For citations:
Mareev Yu.V., Gilarevsky S.R., Begrambekova Yu.L., Lopatin Yu.M., Garganeeva A.A., Duplyakov D.V., Kobalava Zh.D., Golukhova E.Z., Koziolova N.A., Panov А.V., Lelyavina Т.А., Drapkina O.M., Mareev V.Yu. Expert consensus regarding treatment of iron deficiency in stable and decompensated patients with heart failure. Kardiologiia. 2021;61(4):73-78. (In Russ.) https://doi.org/10.18087/cardio.2021.4.n1639