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Expert consensus regarding treatment of iron deficiency in stable and decompensated patients with heart failure

https://doi.org/10.18087/cardio.2021.4.n1639

Abstract

In recent years there has been significant interest in treating iron deficiency (ID) in patients with heart failure (HF) due to its high prevalence and detrimental effects in this population. As stated in the 2020 Russain HF guidelines, Intravenous ferric carboxymaltose remains the only proven therapy for ID.
This document was prompted by the results from the recent AFFIRM-AHF trial which demonstrates that treatment of ID after acute HF decompensation reduces the risk of future decompensations. 
Experts have concluded that in HF patients with acute decompensation, a left ventricular ejection fraction of < 50% and ID, Intravenous ferric carboxymaltose reduces future HF hospitalisations. Patients with stable HF may also benefit from treatment of ID to improve quality of life and alleviate symptoms.  It is, therefore, reasonable to screen for and treat ID in patients with HF.

About the Authors

Yu. V. Mareev
National Medical Research Centre for Therapy and Preventive Medicine, Moscow, Russia Robertson Centre for Biostatistics, Glasgow, Great Britain
Russian Federation

Senior Researcher 



S. R. Gilarevsky
Russian Medical Academy of Postgraduate Education, Moscow, Russia
Russian Federation

Professor of the Department of Clinical Pharmacology and Therapy



Yu. L. Begrambekova
Medical Research and Educational Center of the M. V. Lomonosov Moscow State University, Moscow, Russia Faculty of Fundamental Medicine, Lomonosov Moscow State University, Russia
Russian Federation

Leading Researcher Medical Research and Education Center of Moscow State University M.V. Lomonosova



Yu. M. Lopatin
Volgograd State Medical University, Volgograd, Russia
Russian Federation

Head of the Department of Cardiology, Cardiovascular and Thoracic Surgery



A. A. Garganeeva
Research Institute for Cardiology, Siberian State Medical University, Tomsk National Research Medical Center, Russian Academy of Sciences
Russian Federation

Head of the Department of General Clinical Cardiology and Epidemiology of Cardiovascular Diseases



D. V. Duplyakov
Samara Regional Clinical Cardiological Dispensary, Russia Samara State Medical University, Samara, Russia
Russian Federation

Deputy Chief Physician for Medical Affair



Zh. D. Kobalava
Russian State University of Peoples' Friendship, Moscow, Russia
Russian Federation

Head of the Department of Internal Medicine and Clinical Pharmacology, Faculty of Advanced Training of Medical Workers



E. Z. Golukhova
Bakulev National Medical Research Center of Cardiovascular Surgery, Moscow, Russia
Russian Federation

Academic of the Russian Academy of Sciences, Ph.D. Med., Professor, Acting Head of A.N. Bakulev National Medical Scientific Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation



N. A. Koziolova
Perm State Medical University named after Academician E.A. Wagner, Perm, Russia
Russian Federation

Head of the Department of Propedeutics of Internal Diseases No. 2



А. V. Panov
V.A. Almazov National Medical Research Center, Saint Petersburg, Russia
Russian Federation

Head of the Research Department of Ischemic Heart Disease,



Т. А. Lelyavina
V.A. Almazov National Medical Research Center, Saint Petersburg, Russia
Russian Federation

Leading Researcher, Laboratory of High-Tech Methods for the Treatment of Heart Failure



O. M. Drapkina
National Medical Research Centre for Therapy and Preventive Medicine, Moscow, Russia
Russian Federation

Director



V. Yu. Mareev
Medical Research and Educational Center of the M. V. Lomonosov Moscow State University, Moscow, Russia Faculty of Fundamental Medicine, Lomonosov Moscow State University, Russia
Russian Federation

Chief Researcher Medical Research and Education Center of Moscow State University M.V. Lomonosova, Moscow, Russia



References

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Review

For citations:


Mareev Yu.V., Gilarevsky S.R., Begrambekova Yu.L., Lopatin Yu.M., Garganeeva A.A., Duplyakov D.V., Kobalava Zh.D., Golukhova E.Z., Koziolova N.A., Panov А.V., Lelyavina Т.А., Drapkina O.M., Mareev V.Yu. Expert consensus regarding treatment of iron deficiency in stable and decompensated patients with heart failure. Kardiologiia. 2021;61(4):73-78. (In Russ.) https://doi.org/10.18087/cardio.2021.4.n1639

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ISSN 2412-5660 (Online)