Frailty syndrome as an independent predictor of adverse prognosis in patients with chronic heart failure
https://doi.org/10.18087/cardio.2022.3.n1206
Abstract
This review presents results of clinical studies of senile asthenia (“fragility”) syndrome and chronic heart failure (CHF). Recent reports of the “fragility” prevalence in patients with CHF are described. The review presents specific features of pathophysiological pathways underlying the development of both senile asthenia syndrome and CHF; the role of “fragility” in the progression and complications of CHF is addressed. Senile asthenia syndrome associated with CHF is regarded as an independent predictor of unfavorable prognosis and high mortality in this patient category. The authors concluded that methods for “fragility” evaluation in CHF patients followed by risk stratification and selection of individual management tactics should be implemented in clinical practice.
Supporting agencies: This study was supported by a comprehensive program of basic scientific research of the Siberian Branch of the Russian Academy of Sciences as a part of the basic topic of the Research Institute for Complex Issues of Cardiovascular Diseases # 0546‑2019‑0003, “Multifactorial Atherosclerosis and Comorbidities. Features of Diagnostics and Risk Management in the Conditions of a Large Industrial Region of Siberia”. No conflict of interest is reported.
About the Authors
K. E. Krivoshapova
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Russian Federation
researcher at the Laboratory of Comorbidities in Cardiovascular Disease, Ph. D.
Kemerovo
E. A. Vegner
Kemerovo State Medical
Russian Federation
Russian Federation
PhD student at the Department of Cardiology and Cardiovascular Surgery
Kemerovo
Olga L. Barbarash
Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical
Russian Federation
Russian Federation
Director of Institution; Chairperson of the Department of Cardiology and Cardiovascular Surgery, PhD, Professor, Corresponding Member of the RAS
Kemerovo
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Krivoshapova K.E., Vegner E.A., Barbarash O.L. Frailty syndrome as an independent predictor of adverse prognosis in patients with chronic heart failure. Kardiologiia. 2022;62(3):89-96. (In Russ.) https://doi.org/10.18087/cardio.2022.3.n1206
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