Use of Statins, Anticoagulants, Antiaggregants and Antiarrhythmic Drugs in Patients With COVID-19. The Agreed Experts’ Position of Russian Society of Cardiology, Eurasian Association of Therapists, National Society on Atherothrombosis, Societies of Experts in Urgent Cardiology, Eurasian Arrhythmology Association
Ye. V. Shlyakhto,
G. P. Arutyunov,
Yu. N. Belenkov,
E. I. Tarlovskaya,
A. O. Konradi,
E. P. Panchenko,
I. S. Yavelov,
S. N. Tereshchenko,
A. V. Ardashev,
A. G. Arutyunov,
N. Yu. Grigorieva,
G. A. Dzhunusbekova,
O. M. Drapkina,
N. A. Koziolova,
A. L. Komarov,
E. S. Kropacheva,
S. V. Malchikova,
N. P. Mitkovskaya,
Ya. A. Orlova,
M. M. Petrova,
A. P. Rebrov,
H. Sisakian,
V. V. Skibitsky,
A. B. Sugraliyev,
I. V. Fomin,
A. I. Chesnikova,
I. I. Shaposhnik,
E. G. Zhelyakov,
S. G. Kanorskii,
L. V. Kolotsey,
V. A. Snezhitskiy https://doi.org/10.18087/cardio.2020.6.n1180
Abstract
This article discusses relevant aspects in the treatment of patients with COVID-19. Up-to-date information about principles for administration of statins, antithrombotics, and antiarrhythmics is presented. The authors addressed in detail specific features of reversing heart rhythm disorders in patients with coronavirus infection and the interaction of antiarrhythmic and antiviral drugs. Recommendations are provided for outpatient and inpatient antithrombotic therapy for patients with COVID-19. Issues of antithrombotic and antiviral drug interaction are discussed.
Keywords
COVID-19,
SARS-Cov-2,
statins,
coagulopathy,
antithrombotics,
antiplatelets,
myocardial infarction,
arrhythmias,
antiarrhythmics
Supporting agencies: No Conflict of Interest Authors Claimed
About the Authors
Ye. V. Shlyakhto
Almazov National Medical Research Centre of Ministry of Healthcare of Russia, Saint- Petersburg
Russian Federation
academician of RAS, PhD, General Director
Russian Federation
academician of RAS, PhD, General Director
G. P. Arutyunov
Pirogov Russian National Research Medical University, Moscow
Russian Federation
corresponding member of the RAS, PhD, head of the Department of internal diseases and General physiotherapy
Russian Federation
corresponding member of the RAS, PhD, head of the Department of internal diseases and General physiotherapy
Yu. N. Belenkov
First Moscow state medical University I. M. Sechenov, Moscow
Russian Federation
academician of RAS, MD, PhD, head of Department of hospital therapy №1 medical faculty
Russian Federation
academician of RAS, MD, PhD, head of Department of hospital therapy №1 medical faculty
E. I. Tarlovskaya
Volga Research Medical University, Nizhny Novgorod
Russian Federation
MD, PhD, Professor, head of the Department of therapy and cardiology
Russian Federation
MD, PhD, Professor, head of the Department of therapy and cardiology
A. O. Konradi
National research medical center V. A. Almazov of Ministry of Healthcare of Russia, Saint-Petersburg
Russian Federation
corresponding member of the Russian Academy of Sciences. MD, PhD, Professor, Deputy General Director of scientific work Director
Russian Federation
corresponding member of the Russian Academy of Sciences. MD, PhD, Professor, Deputy General Director of scientific work Director
E. P. Panchenko
National Medical Research Center of Cardiology, Moscow
professor, MD, PhD, the head of the Departmen Clinical Problems of Atherothrombosis t
professor, MD, PhD, the head of the Departmen Clinical Problems of Atherothrombosis t
I. S. Yavelov
National Medical Research Center for Therapy and Preventive Medicine, Moscow
MD, PhD, leading researcher of the Department of clinical cardiology
MD, PhD, leading researcher of the Department of clinical cardiology
S. N. Tereshchenko
National Medical Research Center of Cardiology, Moscow
Russian Federation
MD, Professor, head of the Department of myocardial diseases and heart failure
Russian Federation
MD, Professor, head of the Department of myocardial diseases and heart failure
A. V. Ardashev
Lomonosov Moscow State University, Moscow
Russian Federation
MD, PhD, head of the Department of rhythm and conduction disorders, Medical research and educational center
Russian Federation
MD, PhD, head of the Department of rhythm and conduction disorders, Medical research and educational center
A. G. Arutyunov
Pirogov Russian National Research Medical University, Moscow
Russian Federation
MD, PhD, Professor Secretary General - Association “Eurasian Association of Therapists” , Moscow
Russian Federation
MD, PhD, Professor Secretary General - Association “Eurasian Association of Therapists” , Moscow
N. Yu. Grigorieva
Volga Research Medical University, Nizhny Novgorod
Russian Federation
MD, PhD, associate Professor, head of the Department of faculty and polyclinic therapy
Russian Federation
MD, PhD, associate Professor, head of the Department of faculty and polyclinic therapy
G. A. Dzhunusbekova
Kazakh Medical University of Contnuing Education, Alma-Atyu
Kazakhstan
MD, PhD, Professor, Head of Cardiology Department
Kazakhstan
MD, PhD, Professor, Head of Cardiology Department
O. M. Drapkina
National Center for Therapy and Preventive Medicine, Moscow
Russian Federation
MD, PhD, Professor, Director
Russian Federation
MD, PhD, Professor, Director
N. A. Koziolova
State funded educational institution of the highest education “E.A. Wagner Perm State Medical University” Public Health Ministry of Russian Federation, Perm
Russian Federation
MD, PhD, Professor, Head of the Department of Propaedeutics of Internal Diseases №2
Russian Federation
MD, PhD, Professor, Head of the Department of Propaedeutics of Internal Diseases №2
A. L. Komarov
Department of clinical problems of atherothrombosis "NMIC cardiology" of the Ministry of health of the Russian Federation, Moscow
Russian Federation
MD, PhD, leading researcher
Russian Federation
MD, PhD, leading researcher
E. S. Kropacheva
National Medical Research Centre of Cardiology, Moscow
Russian Federation
MD, PhD Department of clinical problems of atherotrombosis
Russian Federation
MD, PhD Department of clinical problems of atherotrombosis
S. V. Malchikova
Kirov State Medical University Kirov State Medical University, Kirov
Russian Federation
MD, PhD, Professor of the Department of Нospital Therapy
Russian Federation
MD, PhD, Professor of the Department of Нospital Therapy
N. P. Mitkovskaya
Cardiology and internal diseases of BSMU, Republic of Belarus, Minsk
Belarus
MD, PhD, Professor, head of the Department
Belarus
MD, PhD, Professor, head of the Department
Ya. A. Orlova
Lomonosov Moscow State University, Moscow
Russian Federation
MD, PhD, Professor, Head of the Department of Age-associated diseases, Medical Scientific and Educational Center
Russian Federation
MD, PhD, Professor, Head of the Department of Age-associated diseases, Medical Scientific and Educational Center
M. M. Petrova
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky, Krasnoyarsk
Russian Federation
DM, Professor, Head of the Department of Polyclinic Therapy and Family Medicine with a Course of Postgraduate Education
Russian Federation
DM, Professor, Head of the Department of Polyclinic Therapy and Family Medicine with a Course of Postgraduate Education
A. P. Rebrov
Saratov State Medical University named after V.I. Razumovsky, Saratov
Russian Federation
MD, professor at the Department of the Internal Medicine
Russian Federation
MD, professor at the Department of the Internal Medicine
H. Sisakian
Yerevan State Medical University, Yerevan
Armenia
MD, PhD, Professor, head of the Department of Cardiology
Armenia
MD, PhD, Professor, head of the Department of Cardiology
V. V. Skibitsky
Cuban State Medical University, Krasnodar
Russian Federation
MD, PhD, Professor, head of the Department of hospital therapy
Russian Federation
MD, PhD, Professor, head of the Department of hospital therapy
A. B. Sugraliyev
Asfendiyarov Kazakh National Medical University, Alma-Atyu
Kazakhstan
head of Internal Disease Unit
Kazakhstan
head of Internal Disease Unit
I. V. Fomin
Volga Research Medical University, Nizhny Novgorod
Russian Federation
MD, PhD, associate Professor, head of the Department of hospital therapy
Russian Federation
MD, PhD, associate Professor, head of the Department of hospital therapy
A. I. Chesnikova
Rostov State Medical University, Rostov-on-Don
Russian Federation
MD, PhD, Professor, Professor in the Department of Internal Medicine №.1
Russian Federation
MD, PhD, Professor, Professor in the Department of Internal Medicine №.1
I. I. Shaposhnik
South Ural state medical University, Chelyabinsk
Russian Federation
MD, PhD, Professor. head of the Department of the propaedeutics of internal diseases
Russian Federation
MD, PhD, Professor. head of the Department of the propaedeutics of internal diseases
E. G. Zhelyakov
Lomonosov Moscow State University, Moscow
Russian Federation
MD, Medical Research and Education Center, Department of Arrhythmology
Russian Federation
MD, Medical Research and Education Center, Department of Arrhythmology
S. G. Kanorskii
Kuban State Medical University of the Ministry of Healthcare of the Russian Federation, Krasnodar
Russian Federation
MD, Professor, Head of the Department of Internal Medicine № 2 of the Faculty of Advanced Training and Professional Retraining at the Federal State Budgetary Educational Institution of Higher Education
Russian Federation
MD, Professor, Head of the Department of Internal Medicine № 2 of the Faculty of Advanced Training and Professional Retraining at the Federal State Budgetary Educational Institution of Higher Education
L. V. Kolotsey
Grodno State Medical University, Grodno
Belarus
PhD, research assistant
Belarus
PhD, research assistant
V. A. Snezhitskiy
Grodno State Medical University, Grodno
Belarus
MD, professor,Head of the Department of Internal diseases and Therapy, Rector
Belarus
MD, professor,Head of the Department of Internal diseases and Therapy, Rector
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Review
For citations:
Shlyakhto Ye.V., Arutyunov G.P., Belenkov Yu.N., Tarlovskaya E.I., Konradi A.O., Panchenko E.P., Yavelov I.S., Tereshchenko S.N., Ardashev A.V., Arutyunov A.G., Grigorieva N.Yu., Dzhunusbekova G.A., Drapkina O.M., Koziolova N.A., Komarov A.L., Kropacheva E.S., Malchikova S.V., Mitkovskaya N.P., Orlova Ya.A., Petrova M.M., Rebrov A.P., Sisakian H., Skibitsky V.V., Sugraliyev A.B., Fomin I.V., Chesnikova A.I., Shaposhnik I.I., Zhelyakov E.G., Kanorskii S.G., Kolotsey L.V., Snezhitskiy V.A. Use of Statins, Anticoagulants, Antiaggregants and Antiarrhythmic Drugs in Patients With COVID-19. The Agreed Experts’ Position of Russian Society of Cardiology, Eurasian Association of Therapists, National Society on Atherothrombosis, Societies of Experts in Urgent Cardiology, Eurasian Arrhythmology Association. Kardiologiia. 2020;60(6):4–14. (In Russ.) https://doi.org/10.18087/cardio.2020.6.n1180
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