Role of age, comorbidity and renin- angiotensin-aldosterone system in COVID-19. Effects of ACE inhibitors and angiotensin receptor blockers
https://doi.org/10.18087/cardio.2020.4.n1122
Abstract
The review addressed the relationship of coronavirus disease 2019 (COVID-19) with functioning of the renin-angiotensin-aldosterone axis and the causes for unfavorable prognosis depending on patients’ age and comorbidities. The authors discussed in detail potential effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists on the risk of infection and the course of COVID-2019 as well as the effect of SARS-COV2 virus on the cardiovascular system.
About the Authors
Yu. V. Mareev
National Medical Research Center for Therapy and Preventive Medicine, Petroverigsky Per. 10, Bldg. 3, Moscow 101990
Russian Federation
Russian Federation
V. Yu. Mareev
Medical Scientific-Educational Canter of MSU n. a. M. V. Lomonosov, Moscow
Russian Federation
ScD, professor
Russian Federation
ScD, professor
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Review
For citations:
Mareev Yu.V., Mareev V.Yu. Role of age, comorbidity and renin- angiotensin-aldosterone system in COVID-19. Effects of ACE inhibitors and angiotensin receptor blockers. Kardiologiia. 2020;60(4):4-9. https://doi.org/10.18087/cardio.2020.4.n1122
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