Case of lifetime diagnosis of isolated primary amyloidosis of the heart
I. V. Demko,
L. I. Pelinovskaya,
A. Yu. Kraposhina,
V. E. Selin,
A. E. Ryazanov,
Ya. I. Verigo,
V. A. Mosina https://doi.org/10.18087/cardio.2022.1.n1049
Abstract
The article presents a case of intravital diagnosis of a rare heart disease, isolated primary amyloidosis. The clinical onset of the disease was heart failure (HF) that was resistant to treatment; chemotherapy was ineffective and was poorly tolerated by the patient. The diagnostics was based on a combination of refractory HF and changes in echocardiography data (atrial dilatation, small size of the left ventricular cavity, interventricular septal hypertrophy with the presence of hyperechoic inclusions of the “granular fluorescence” type), and changes detected by contrast-enhanced cardiac magnetic resonance imaging. The diagnosis of amyloidosis was confirmed by results of pathohistological examination of the material obtained during autopsy.
Supporting agencies: No conflict of interest is reported.
About the Authors
I. V. Demko
Krasnoyarsk state medical university by prof. Voino-Yasenetsky V.F., Krasnoyarsk
Russian Federation
Russian Federation
MD, PhD, professor, Head, Department of internal diseases and immunology with a course of postgraduate education
L. I. Pelinovskaya
Krasnoyarsk state medical university by prof. Voino-Yasenetsky V.F., Krasnoyarsk
Russian Federation
Russian Federation
PhD, assistent, Department of internal diseases and immunology with a course of postgraduate education
A. Yu. Kraposhina
Krasnoyarsk state medical university by prof. Voino-Yasenetsky V.F., Krasnoyarsk
Russian Federation
Russian Federation
PhD, associate professor, Department of internal diseases and immunology with a course of postgraduate education
V. E. Selin
Krasnoyarsk state medical university by prof. Voino-Yasenetsky V.F., Krasnoyarsk
Russian Federation
Russian Federation
Assistant, Department of pathological anatomy named after prof. P.G. Podzolkova
A. E. Ryazanov
Regional clinical hospital, Krasnoyarsk
Russian Federation
Russian Federation
Head, Cardiology department No. 1
Ya. I. Verigo
Regional clinical hospital, Krasnoyarsk
Russian Federation
Russian Federation
PhD, doctor cardiologist, Cardiology department № 1
V. A. Mosina
Krasnoyarsk state medical university by prof. Voino-Yasenetsky V.F., Krasnoyarsk
Russian Federation
Russian Federation
PhD, associate professor, Department of internal diseases and immunology with a course of postgraduate education
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Review
For citations:
Demko I.V., Pelinovskaya L.I., Kraposhina A.Yu., Selin V.E., Ryazanov A.E., Verigo Ya.I., Mosina V.A. Case of lifetime diagnosis of isolated primary amyloidosis of the heart. Kardiologiia. 2022;62(1):106-108. (In Russ.) https://doi.org/10.18087/cardio.2022.1.n1049
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