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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2020.9.n910</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-910</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Роль модифицируемых сердечно-сосудистых факторов риска в возникновении онкологических заболеваний</article-title><trans-title-group xml:lang="en"><trans-title>Role of modified cardiovascular risk factors in development of oncologic diseases</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5294-1273</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зволинская</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvolinskaya</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.,ведущий научный сотрудник лаборатории междисциплинарного подхода в профилактике хронических неинфекционных заболеваний ФГБУ НМИЦ ПМ МЗ РФ</p><p>SPIN-код: 2746-5408</p></bio><bio xml:lang="en"><p>PhD., main researcher of Department of Rehabilitation and Secondary Prevention of Combined Pathology of National Medical Research Center for Preventive Medicine of the Ministry of Healthcare of the Russian Federation</p><p> </p></bio><email xlink:type="simple">ringva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7131-8049</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамедов</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamedov</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заведующий лабораторией по разработке междисциплинарного подхода в профилактике хронических неинфекционных заболеваний ФГБУ НМИЦ ПМ МЗ РФ, доктор медицинских наук, профессор</p><p>SPIN-код: 6631-9718</p></bio><bio xml:lang="en"><p>PhD., MD, head of Department of Rehabilitation and Secondary Prevention of Combined Pathology of National Medical Research Center for Preventive Medicine of the Ministry of Healthcare of the Russian Federation</p></bio><email xlink:type="simple">mmamedov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2459-7273</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потиевская</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Potievskaya</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., главный научный сотрудник ФГБУ«НМИЦ радиологии» Минздрава России</p></bio><bio xml:lang="en"><p>PhD., MD, chief researcher of Federal State Budgetary Institution National Medical Radiology Research Center of the Health Ministry of Russia</p></bio><email xlink:type="simple">vera.pot@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7689-6032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., директор Медицинского радиологического научного центра им. А.Ф.Цыба – филиала ФГБУ«НМИЦ радиологии» Минздрава России</p></bio><bio xml:lang="en"><p>PhD., MD, director of A.F. Tsyb Medical Radiological Research Center the branch of Federal State Budgetary Institution National Medical Radiology Research Center of the Health Ministry of Russia</p></bio><email xlink:type="simple">khrapovama@nmirc.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8784-8415</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>академик РАН, генеральный директор ФГБУ «НМИЦ радиологии»  Минздрава России</p></bio><bio xml:lang="en"><p>PhD., MD, Academician of Russian Academy of Science, General director of Federal State Budgetary Institution National Medical Radiology Research Center of the Health Ministry of Russia</p></bio><email xlink:type="simple">dr89031990702@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ профилактической медицины» Минздрава РФ, Москва, Россия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthcare, Moscow, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ радиологии» Минздрава РФ, Москва, Россия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Radiology Research Center of the Ministry of Healthcare, Moscow, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>«МРНЦ им. А. Ф. Цыба», ФГБУ «НМИЦ радиологии» Минздрава РФ, Обнинск, Россия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Radiological Research Center the branch of National Medical Radiology Research Center of the Ministry of Healthcare, Obninsk, Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>14</day><month>10</month><year>2020</year></pub-date><volume>60</volume><issue>9</issue><fpage>110</fpage><lpage>121</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/910">https://cardio.elpub.ru/jour/article/view/910</self-uri><abstract><p>Сердечно-сосудистые заболевания (ССЗ) и онкологические заболевания (ОЗ) являются ведущими причинами смерти во всем мире и обусловливают весомую нагрузку на экономику многих стран в плане инвалидизации населения и смертности. Для увеличения продолжительности и качества жизни пациентов, выживших после перенесенного онкологического заболевания, а также предупреждения возникновения коморбидной патологии, правильного ведения и корректного информирования пациентов о факторах риска и модификации образа жизни необходимо иметь четкое представление об общности механизмов возникновения ССЗ и рака. Известны общие факторы риска для обеих групп заболеваний: курение, ожирение, сахарный диабет, алкоголь, погрешности в питании и др. Наряду с этим одну из центральных ролей может играть воспаление, так как оно способствует возникновению обеих групп заболеваний и встречается в условиях ожирения, сахарного диабета, артериальной гипертензии и дислипидемии. Дальнейшее понимание взаимодействия между ССЗ и раком позволит создать общие эффективные диагностические и профилактические стратегии, а также безопасные подходы к лечению.</p></abstract><trans-abstract xml:lang="en"><sec><title>Cardiovascular (CVD) and oncological diseases (OD) are the main causes of death worldwide and account for a heavy burden on economy, disability and mortality in many countries. Clear understanding of the mechanisms shared by CVD and cancer is important for increasing the life span and quality of life in cancer survivors as well as for preventing comorbidities and correct instructing the patients about risk factors and lifestyle modifications. Both groups of diseases share risk factors, including smoking, obesity, diabetes mellitus, alcohol consumption, unhealthy diet, etc. Along with these factors, inflammation may play a key role as it promotes both types of diseases and accompanies obesity, diabetes mellitus, arterial hypertension, and dyslipidemia. Better understanding of the interaction between CVD and cancer will allow creating common effective diagnostic and preventive strategies and safe approaches to the treatment.</title></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Факторы риска</kwd><kwd>сердечно-сосудистые заболевания</kwd><kwd>онкология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Risk factors</kwd><kwd>cardiovascular diseases</kwd><kwd>cancer</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Конфликт интересов не заявлен.</funding-statement><funding-statement xml:lang="en">No conflict of interest is reported.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. World health statistics 2018: monitoring health for the SDGs. 2018. ISBN 978-92-4-156558-5</mixed-citation><mixed-citation xml:lang="en">World Health Organization. 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