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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2020.3.n881</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-881</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Инфаркт миокарда без признаков обструктивного атеросклероза коронарных артерий</article-title><trans-title-group xml:lang="en"><trans-title>Myocardial infarction with nonobstructive coronary arteries</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шерашов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sherashov</surname><given-names>Andrey V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отделения интенсивной терапии и реанимации для пациентов с инфарктом миокарда</p></bio><bio xml:lang="en"><p>cardiologist of intensive coronary care unit</p></bio><email xlink:type="simple">sherashovmd@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующая отделением интенсивной терапии и реанимации для пациентов с инфарктом миокарда, к. м. н.</p></bio><bio xml:lang="en"><p>chief of of intensive coronary care unit, Ph.D.</p></bio><email xlink:type="simple">a.s.shilova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Першина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Pershina</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>руководитель центра лучевой диагностики, к.м.н.</p></bio><bio xml:lang="en"><p>chief of X-ray, CT and MRI department, Ph.D.</p></bio><email xlink:type="simple">pershina86@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8209-2791</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щекочихин</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shchekochikhin</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кардиолог отделения кардиологии</p><p> </p></bio><bio xml:lang="en"><p>cardiologist of cardiology department</p></bio><email xlink:type="simple">agishm@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Свет</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Svet</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>главный врач, к.м.н.</p></bio><bio xml:lang="en"><p>chief physician</p></bio><email xlink:type="simple">ssvetalex69@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2870-3301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гиляров</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gilyarov</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заместитель главного врача по терапевтической помощи</p><p>заведующий кафедрой интервенционной кардиологии и кардиореабилитации, д. м. н.</p></bio><bio xml:lang="en"><p>chief of department of interventional cardiology and cardiorheabilitation</p><p>deputy chief physician, Ph.D.</p><p> </p></bio><email xlink:type="simple">gilarov@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГКБ № 1 им. Н. И. Пирогова Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital #1 named after N. I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГКБ № 1 им. Н. И. Пирогова Департамента здравоохранения г. Москвы&#13;
Российский национальный исследовательский медицинский университет им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital #1 named after N. I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГКБ № 1 им. Н. И. Пирогова Департамента здравоохранения г. Москвы&#13;
Российский национальный исследовательский медицинский университет им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital #1 named after N. I. Pirogov&#13;
First Moscow State Medical University named after I. M. Sechenov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГКБ № 1 им. Н. И. Пирогова Департамента здравоохранения г. Москвы&#13;
Российский национальный исследовательский медицинский университет им. Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian National Research Medical Univercity named after N. I. Pirogov&#13;
City clinical hospital #1 named after N. I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>18</day><month>03</month><year>2020</year></pub-date><volume>60</volume><issue>3</issue><fpage>89</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/881">https://cardio.elpub.ru/jour/article/view/881</self-uri><abstract><p>В обзоре рассматривается сравнительно новая проблема – инфаркт миокарда без обструкции коронарных артерий (ИМбоКА). По современным представлениям, почти 6 % случаев всех инфарктов миокарда (ИМ) могут быть ИМбоКА. При этом данный термин может применяться как «рабочий диагноз» на момент процесса дообследования, так и как окончательный диагноз после выяснения причин каждого отдельного случая. Ввиду того что некоторые варианты кардиальной, в том числе некоронарной, патологии могут быть по ряду признаков схожи с ИМ, возникает потребность уточнения каждого отдельного случая ИМбоКА. Среди основных причин данного состояния следует выделить: вазоспазм, тромбоэмболия КА, спонтанная диссекция КА, разрыв эксцентричной атеркослеротической бляшки КА и др. Диагностика ИМбоКА включает набор диагностических тестов, необходимых для верификации диагноза ИМ, согласно 4-му универсальному определению ИМ, так и специфических исследований, направленных на уточнение этиологии данного состояния. Особую роль в дифференциальной диагностике играет магнитно-резонансная томография (МРТ) миокарда с внутривенным контрастным усилением гадолинием, позволяющая отличить инфаркт от неишемического поражения миокарда различного генеза. Также немаловажным являются способы внутрисосудистой визуализации, такие как оптическая когерентная томография (ОКТ), внутрисосудистое ультразвуковое исследование (ВСУЗИ). Общепринятые рекомендации по терапии данной патологии согласно текущим представлениям отсутствуют, однако очевидно то, что возможности лечения ИМбоКА и прогноз зависят от выявленной причины в каждом отдельно взятом случае заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The review focused on a relatively new issue, myocardial infarction with non-obstructive coronary arteries (MINOCA). According to current ideas, almost 6% of all myocardial infarction (MI) cases may be MINOCA. This term can be used both as a “working diagnosis” at the time of further evaluation and a final diagnosis after establishing a cause for each specific case. Since some variants of cardiac, including non-coronary, pathology may be similar to MI in a number of signs, each individual case of MINOCA requires specification. Among major causes for this condition are vasospasm, CA embolism, spontaneous CA dissection, rupture of an eccentric atherosclerotic plaque in a CA, etc. Diagnostics of MINOCA includes both a set of diagnostic tests for verification of the MI diagnosis according to the Fourth Universal Definition of MI and specific studies for elaboration of the disease etiology. A special role in differential diagnostics belongs to gadolinium-enhanced magnetic-resonance imaging (MRI) of the myocardium, which allows to distinguish between MI and non-ischemic myocardial injury of different genesis. Methods of intravascular visualization, such as optical coherence tomography (OCT) and intravascular ultrasound are also important. Commonly accepted guidelines on the treatment of this pathology consistent with current ideas are not available. However, it is obvious that therapeutic possibilities and prognosis for MINOCA depend on the identified cause in each individual case.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Инфаркт миокарда</kwd><kwd>инфаркт миокарда без обструкции коронарных артерий</kwd><kwd>патогенез</kwd><kwd>прогноз</kwd><kwd>магнитно-резонансная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Myocardial infarction</kwd><kwd>myocardial infarction with non-obstructive coronary arteries</kwd><kwd>pathogenesis</kwd><kwd>prog­­nosis</kwd><kwd>magnetic resonance imaging</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">грант РФФИ от 2018 г. 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