cardioКардиологияKardiologiia0022-90402412-5660Kardiomag10.18087/cardio.2019.7.10263cardio-751Research ArticleПРАКТИЧЕСКАЯ КАРДИОЛОГИЯ ПРИЛОЖЕНИЕ ДЛЯ ПРАКТИЧЕСКИХ ВРАЧЕЙ. КЛИНИЧЕСКИЕ СЕМИНАРЫPRACTICAL CARDIOLOGY SUPPLEMENT FOR PRACTISING PHYSICIANS. CLINICAL SEMINARSАнализ выдыхаемого воздуха в диагностике сердечно-сосудистых заболеванийExhaled Breath Analysis in Diagnostics of Cardiovascular DiseasesБыковаА. А.BykovaA. A.

Москва

Bykova Aleksandra A. – PhD, assistant. 

Moscow

aabykowa@yandex.ruМалиновскаяЛ. К.MalinovskayaL. K.

Москва

Moscow

ЧомахидзеП. Ш.ChomakhidzeP. Sh.

Москва

Moscow

ТрушинаО. В.TrushinaO. V.

Москва

Moscow

ШалтаеваЮ. Р.ShaltaevaY. R.

Москва

Moscow

БеляковВ. В.BelyakovV. V.

Москва

Moscow

ГоловинА. В.GolovinA. V.

Москва

Moscow

ПершенковВ. С.PershenkovV. S.

Москва

Moscow

СыркинА. Л.SyrkinA. L.

Москва

Moscow

БетелинВ. Б.BetelinV. B.

Москва

Moscow

КопыловФ. Ю.KopylovPh. Yu.

Москва

Moscow

ФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет); ФГУ «Федеральный научный центр НИИ системных исследований» РАНРоссияSechenov First Moscow State Medical University (Sechenov University); Scientific Research Institute for System AnalysisRussian FederationФГАОУ ВО Первый Московский государственный медицинский университет им. И. М. Сеченова Минздрава России (Сеченовский Университет)РоссияSechenov First Moscow State Medical University (Sechenov University)Russian FederationФГАОУ ВПО «Национальный исследовательский ядерный университет «МИФИ»РоссияNational Research Nuclear University MEPhI (Moscow Engineering Physics Institute)Russian FederationФГУ «Федеральный научный центр НИИ системных исследований» РАНРоссияScientific Research Institute for System AnalysisRussian Federation2019190720195976167Copyright © Kardiomag, 20192019KardiomagKardiomaghttps://cardio.elpub.ru/jour/about/submissions#copyrightNoticehttps://cardio.elpub.ru/jour/article/view/751

Анализ выдыхаемого воздуха – новый перспективный метод диагностики различных заболеваний. Состав выдыхаемого воздуха различен в норме и при патологии. В обзоре рассматриваются некоторые вещества, содержание которых меняется при сердечно-сосудистых заболеваниях, – это пентан, изопрен, окись углерода и триметиламин. Современное развитие технологий позволяет перенести анализ выдыхаемого воздуха из научно-исследовательских лабораторий в клиническую практику. Таким образом, в арсенале врачей появился новый инструмент для скрининга различных сердечно-сосудистых заболеваний в режиме реального времени.

Exhaled breath analysis is a novel tool for diagnostics of different diseases. Taking into account the secretory function of the lungs, the composition of exhaled breath is different in physiological and pathological conditions. In this review we consider of some substances which content vary in cardiovascular diseases – pentane, isoprene, carbon monoxide and trimethylamine. Modern technologies allow to move the analysis of exhaled breath from research laboratories into clinical practice. Thus, a new tool for real time of screening various cardiovascular diseases has appeared in the arsenal of physicians.

анализ выдыхаемого воздухасердечно-сосудистые заболеванияхроническая сердечная недостаточностьацетонпентанокись углеродаизопрентриметиламинexhaled breath analysiscardiovascular diseaseheart failureacetonepentanecarbon monoxideisoprenetrimethylamineПубликация выполнена в рамках государственного задания ФГУ ФНЦ «НИИСИ» РАН (проведение фундаментальных научных исследований) по теме № 0065‑2018‑0116 «Применение метода протонной масс-спектрометрии в диагностике различных заболеваний человека» (№АААА‑А18‑118041290150‑4).ReferencesOrganisation mondiale de la santé. Global status report on noncommunicable diseases 2014: attaining the nine global noncommunicable diseases targets; a shared responsibility. - Geneva: World Health Organization; 298 с. ISBN 978-92-4-156485-4Organisation mondiale de la santé. Global status report on noncommunicable diseases 2014: attaining the nine global noncommunicable diseases targets; a shared responsibility. -Geneva: World Health Organization; 298 с. 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The authors declare that there are no conflicts of interest present.