cardioКардиологияKardiologiia0022-90402412-5660Kardiomag10.18087/cardio.2019.5.n493cardio-660Research ArticleПРАКТИЧЕСКАЯ КАРДИОЛОГИЯ ПРИЛОЖЕНИЕ ДЛЯ ПРАКТИЧЕСКИХ ВРАЧЕЙ. КЛИНИЧЕСКИЕ СЕМИНАРЫPRACTICAL CARDIOLOGY SUPPLEMENT FOR PRACTISING PHYSICIANS. CLINICAL SEMINARSАнтитромботическая терапия при фибрилляции предсердий и хронической ишемической болезни сердцаAntithrombotic Therapy in Atrial Fibrillation and Chronic Ischemic Heart DiseaseРычковA. Ю.RychkovA. Yu.ХорьковаН. Ю.KhorkovaN. Yu.

Khorkova Natalia Yu. – MD, scientific researcher

Tomsk

nhorkova@bk.ruТюменский кардиологический научный центр; Томский национальный исследовательский медицинский центр РАНРоссияTyumen Cardiology Research Center; Tomsk National Research Medical Center, Russian Academy of ScienceRussian Federation2019250520195958086Copyright © Kardiomag, 20192019KardiomagKardiomaghttps://cardio.elpub.ru/jour/about/submissions#copyrightNoticehttps://cardio.elpub.ru/jour/article/view/660

Обзор посвящен применению антитромботической терапии у пациентов с фибрилляцией предсердий (ФП) и хронической ишемической болезнью сердца (ИБС). Обсуждаются данные международных регистров, мета-анализов, оценивающих возможность использования пероральных антикоагулянтов (ПОАК) для вторичной профилактики ИБС. Представлены результаты рандомизированных и наблюдательных клинических исследований, свидетельствующих о преимуществах назначения монотерапии ПОАК при сочетании ФП и хронической ИБС. Представлена современная доказательная база преимущества двухкомпонентной антитромботической терапии с применением прямых ПОАК при проведении чрескожных коронарных вмешательств.  

The review is devoted to the use of antithrombotic therapy in patients with atrial fibrillation (AF) and chronic ischemic heart disease (IHD). We discuss data of international registries, meta-analyses assessing possibilities of the use of oral anticoagulants for secondary prevention of IHD. We present here results of randomized and observational clinical studies demonstrating advantages of prescription of monotherapy with oral anticoagulants (OAC) in combination of AF and chronic IHD. Modern evidence base of advantages of dual antithrombotic therapy with the use of direct OAC following percutaneous coronary intervention is also presented.  

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The authors declare that there are no conflicts of interest present.