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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2019.8.n534</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-534</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЕРДЕЧНАЯ НЕДОСТАТОЧНОСТЬ</subject></subj-group></article-categories><title-group><article-title>Легочный застой по данным ультразвукового исследования у пациентов с декомпенсацией сердечной недостаточности</article-title><trans-title-group xml:lang="en"><trans-title>Pulmonary congestion by lung ultrasound in decompensated heart failure: associations, in-hospital changes, prognostic value</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобалава</surname><given-names>Ж. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobalava</surname><given-names>Zh. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жанна Давидовна Кобалава – доктор медицинских наук, профессор, заведующая кафедрой внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева.</p><p>Москва</p><p>9828-5409</p></bio><bio xml:lang="en"><p>Zhanna Davidovna Kobalava - MD, PhD, professor, head of the Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev</p><p>Moscow</p></bio><email xlink:type="simple">zkobalava@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафарова</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Safarova</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Айтен Фуад Кызы Сафарова – доктор медицинских наук, профессор кафедры внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева,  врач отделения функциональной диагностики</p></bio><bio xml:lang="en"><p>Ayten Fuad Kyzy Safarova - MD, PhD, professor at the Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev, doctor in the department of functional diagnostics.</p></bio><email xlink:type="simple">aytensaf@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0013-0660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьева</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Soloveva</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анжела Евгеньевна Соловьева - кандидат медицинских наук, ассистент кафедры внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева</p><p>8120-2909</p><p>Москва</p></bio><bio xml:lang="en"><p>Anzhela Evgenevna Soloveva - MD, PhD, assistant of professor at the Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev.</p><p>Moscow</p></bio><email xlink:type="simple">anzhela.solovieva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кабельо</surname><given-names>Ф.Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Cabello</surname><given-names>F.E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Флора Элиса Кабельо Монтойа - аспирант кафедры внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева</p></bio><bio xml:lang="en"><p>MD, fellow student at the Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev.</p><p>Moscow</p><p> </p></bio><email xlink:type="simple">florinela.cabellomontoya@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мерай</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Meray</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаварова</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Shavarova</surname><given-names>E. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виллевальде</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Villevalde</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Светлана Вадимовна Виллевальде - доктор медицинских наук, профессор, профессор кафедры внутренних болезней с курсом кардиологии и функциональной диагностики имени академика В.С. Моисеева.</p><p>Москва</p><p>1998-3096</p></bio><bio xml:lang="en"><p>Svetlana Vadimovna Villevalde - MD, PhD, professor at the Department of Internal Medicine with the subspecialty of cardiology and functional diagnostics named after V.S. Moiseev</p></bio><email xlink:type="simple">villevaldes@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования Российский университет дружбы народов (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Medicine, Peoples' Friendship University of Russia (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования Российский университет дружбы народов (РУДН); ГБУЗ «ГКБ им. В. В. Виноградова» Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples Friendship University of Russia (RUDN University); Vinogradov City Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования Российский университет дружбы народов (РУДН)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples Friendship University of Russia (RUDN University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>08</day><month>08</month><year>2019</year></pub-date><volume>59</volume><issue>8</issue><fpage>5</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/534">https://cardio.elpub.ru/jour/article/view/534</self-uri><abstract><p>Объективная оценка застоя в легких в клинической практике весьма затруднительна ввиду низкой чувствительности и специфичности клинических и рентгенологических признаков.Цель исследования. Оценка частоты, динамики за время пребывания в стационаре и прогностической ценности признаков легочного застоя у пациентов с декомпенсацией сердечной недостаточности (ДСН) по данным ультразвукового исследования (УЗИ) легких.Материалы и методы. Общепринятое клиническое обследование и УЗИ легких по методике сканирования 8 зон при поступлении и при выписке выполнены у 162 пациентов с ДСН (мужчины 66%, средний возраст 68±12 лет, артериальная гипертония - у 97%, перенесенный инфаркт миокарда - у 44%, фибрилляция предсердий - у 60%, фракция выброса - ФВ 40±14%, ФВ &lt;40% - у 46%, NT-proBNP 4 246 [1741; 6 837] пг/мл). Сумму B-линий ≤5 считали нормальной, 6-15, 16-30 и &gt;30 - как легкий, умеренный и тяжелый легочный застой, соответственно.Результаты. При УЗИ легких исходный легочный застой был диагностирован у всех пациентов (умеренный и тяжелый в 31,5 и 67,3% случаев, соответственно). При выписке нормальный профиль УЗИ легких наблюдался у 48,2% пациентов, у 33,3, 14,8 и 3,7% пациентов сохранялся легкий, умеренный и тяжелый легочный застой соответственно. В многофакторном регрессионном анализе, включившем пол, возраст, ФВ, функциональный класс СН и набухание шейных вен при выписке, сумма В-линий &gt;5 независимо ассоциировалась с более высокой вероятностью смерти от всех причин (относительный риск - ОР 2,86 при 95% доверительном интервале - ДИ от 1,1 до 7,13; р=0,024) в течение года после выписки, сумма B-линий &gt;15 -с более высокой вероятностью повторной госпитализации по поводу СН (ОР 2,83 при 95% ДИ от 1,41 до 5,67; p=0,003).Заключение. За период пребывания в стационаре частота легочного застоя, по данным УЗИ легких, снизилась со 100 до 52%. Сумма B-линий &gt;5 при выписке ассоциировалась с риском смерти от всех причин, сумма B-линий &gt;15 - с более высоким риском повторной госпитализации по поводу СН в течение 12 мес.</p></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Recently lung ultrasound (LUS) based on B-lines measurement has been proposed as an effective tool for assessment of pulmonary congestion (PC) in patients with decompensated heart failure (DHF).</p></sec><sec><title>Objective</title><p>Objective: to assess the incidence, in-hospital changes and prognostic significance of PC assessed by LUS in DHF patients.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. Routine clinical assessment and eight-zone LUS were performed in 162 patients with DHF (men 66%, mean age 68±12 years, hypertension 97%, history of myocardial infarction 44%, atrial fibrillation 60%, ejection fraction [EF] 40±14%, EF&lt;40% 46%, baseline NT-proBNP 4 246 [1741; 6 837] pg/ml). Sum of B-lines ≤5 was considered as normal, 6-15, 16-30 and &gt;30 - as mild, moderate and severe PC, respectively.</p></sec><sec><title>Results</title><p>Results. Using LUS on admission PC was diagnosed in all patients (moderate and severe in 31.5 and 67.3%, respectively). At discharge normal LUS profile was observed in 48.2% of patients. In 33.3, 14.8 and 3.7% of patients PC was mild, moderate, and severe, respectively. According to multivariable Cox regression analysis including age, sex, EF, NYHA functional class, and jugular venous distension sum of B-lines &gt;5 at discharge was associated with higher probability of 12-month all-cause death (hazard ratio [HR] 2.86, 95% confidence interval [CI] 1.15-7.13, p=0.024), sum of B-lines &gt;15 - with higher probability of HF readmission (HR 2.83, 95%CI 1.41-5.67, p=0.003).</p></sec><sec><title>Conclusion</title><p>Conclusion. During hospital stay the incidence of PC as assessed by LUS decreased from 100 to 52% of patients. Sum of B-lines &gt;5 at discharge was independently associated with higher risk of 12-month all-cause death, &gt;15 - with higher risk of 12-month HF readmission.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>лёгочный застой</kwd><kwd>ультразвуковое исследование легких</kwd><kwd>В-линии</kwd><kwd>сердечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary congestion</kwd><kwd>lung ultrasound</kwd><kwd>B lines</kwd><kwd>heart failure</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">легочный застой; ультразвуковое исследование легких; В-линии; сердечная недостаточность</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Мареев В. Ю., Фомин И. В., Агеев Ф. Т., Беграмбекова Ю. Л., Васюк Ю. А., Гарганеева А. А. и др. Клинические рекомендации ОССН -РКО - РНМОТ. 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