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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2020.4.n487</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-487</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Возможности современных биомаркеров для оценки риска развития желудочковых тахиаритмий и внезапной сердечной смерти у больных хронической сердечной недостаточностью</article-title><trans-title-group xml:lang="en"><trans-title>Possibilities of modern biomarkers for assessing the risk of developing ventricular tachyarrhythmias and sudden cardiac death in patients with chronic heart failure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаспарян</surname><given-names>А. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Gasparyan</surname><given-names>A. Zh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант отдела клинической электрофизиологии и рентгенохирургических методов лечения нарушений ритма сердца ИКК им.А.Л.Мясникова ФГБУ «НМИЦ Кардиологии» МЗ РФ. 3-я Черепковская 15А, г. Москва 121552.</p></bio><bio xml:lang="en"/><email xlink:type="simple">armen_ui@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шлевков</surname><given-names>Н. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlevkov</surname><given-names>N. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>старший научный сотрудник лаборатории отдела клинической электрофизиологии и рентгенохирургических методов лечения нарушений ритма сердца ИКК им.А.Л.Мясникова ФГБУ «НМИЦ Кардиологии» МЗ РФ, к.м.н. 3-я Черепковская 15А, г. Москва 121552.</p></bio><bio xml:lang="en"/><email xlink:type="simple">nik.shlevkov@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скворцов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvortsov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">skvortsov00@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ "НМИЦ Кардиологии" МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Organization National Medical Research Center of Cardiology, Ministry of Healthcare Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ "НМИЦ Кардиологии" МЗ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Organization National Medical Research Center of Cardiology, Ministry of Healthcare Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>27</day><month>03</month><year>2020</year></pub-date><volume>60</volume><issue>4</issue><fpage>101</fpage><lpage>108</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/487">https://cardio.elpub.ru/jour/article/view/487</self-uri><abstract><p>Современные биомаркеры позволяют диагностировать широкий спектр патологических процессов, протекающих в организме, оценивать эффективность терапевтических воздействий и прогноз кардиологических больных. Настоящий обзор посвящен возможностям использования N-терминального фрагмента предшественника мозгового натрийуретического пептида (NT-proBNP), растворимого супрессора туморогенности 2-го типа (sST2), галектина-3 и других биомаркеров у больных хронической сердечной недостаточностью для оценки риска развития жизнеугрожающих желудочковых тахиаритмий и возникновения внезапной сердечной смерти.</p></abstract><trans-abstract xml:lang="en"><p>Current biomarkers allow diagnosing a wide array of pathological processes and evaluating effects of therapies and prognosis for cardiological patients. This review focuses on a possibility of using N-terminal pro-brain natriuretic peptide (NT-proBNP), soluble suppressor of tumorigenicity 2 (sST2), galectin-3, and other biomarkers in patients with chronic heart failure for evaluating the risk of life-threatening ventricular tachyarrhythmias and sudden cardiac death.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Биомаркеры</kwd><kwd>NT-proBNP</kwd><kwd>sST2</kwd><kwd>galectin-3</kwd><kwd>хроническая сердечная недостаточность</kwd><kwd>желудочковая тахикардия</kwd><kwd>фибрилляция желудочков</kwd><kwd>внезапная сердечная смерть</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Biomarkers</kwd><kwd>NT-proBNP</kwd><kwd>sST2</kwd><kwd>galectin-3</kwd><kwd>chronic heart failure</kwd><kwd>ventricular tachycardia</kwd><kwd>ventricular fibrillation</kwd><kwd>sudden cardiac death</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Конфликт интересов: не заявлен.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zipes DP. 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