cardioКардиологияKardiologiia0022-90402412-5660Kardiomag10.18087/cardio.n460cardio-460Research ArticleОБЗОРЫREVIEWSГипертрофия миокарда левого желудочка донорского сердца: результаты и перспективыLeft ventricle myocardium hypertrophy of donor heart: the results and outlookhttps://orcid.org/0000-0003-4204-8865ШумаковД. В.ShumakovD. V.

Член-корреспондент РАН, доктор медицинских наук, профессор. Заведующий отделом хирургии сердца и сосудов

SPIN-код: 2545-2978, AuthorID: 96351

sdvtranspl@rambler.ruhttps://orcid.org/0000-0003-2904-5213ДонцовВ. В.DontsovV. V.

Младший научный сотрудник отделения кардиохирургии, врач сердечно-сосудистый хирург

SPIN-код: 8840-7752, AuthorID: 931625

vvdontsov@yandex.ruhttps://orcid.org/0000-0001-7087-5441ЗыбинД. И.ZybinD. I.

Кандидат медицинских наук. Заведующий отделением кардиохирургии

SPIN-код: 5885-2787, AuthorID: 1007673

poison1983@inbox.ruГБУЗ МО «МОНИКИ им.М.Ф. Владимирского»РоссияMoscow Regional Research and Clinical Institute named after M. F. Vladimirsky (MONIKI)Russian Federation201911092019599S1624Copyright © Kardiomag, 20192019KardiomagKardiomaghttps://cardio.elpub.ru/jour/about/submissions#copyrightNoticehttps://cardio.elpub.ru/jour/article/view/460

Гипертрофия миокарда левого желудочка – одно из наиболее частых структурных изменений сердца. Данная статья посвящена оценке современных взглядов на причины возникновения гипертрофии миокарда донорского сердца, показания и противо‑ показания к трансплантации, перспективы расширения пула результативных доноров за счет использования данных сердец. Рассмотрены вопросы посттрансплантационного ремоделирования миокарда донорского сердца, особенности патогенеза, риски возникновения и возможности медикаментозного регулирования гипертрофии миокарда левого желудочка пересажен‑ ного сердца.

Left ventricular hypertrophy – is one of the most frequent structural changes in the heart. This article is devoted to the assessment of modern views on the causes of myocardial hypertrophy of the donor heart, indications and contraindications for the heart trans‑ plantation, the outlook of expanding the pool of effective donors through the use of these hearts. Here are considered the issues of post-transplantation remodeling of the donor heart myocardium, The pathogenesis features, the nascence risk and possibilities of drug regulation of the transplanted heart‘s myocardial hypertrophy of the left ventricle.

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The authors declare that there are no conflicts of interest present.