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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2026.7.n3133</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-3133</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>Продольная систолическая деформация и постсистолическое укорочение миокарда левого желудочка в покое и при стресс-эхокардиографии как предикторы стеноза коронарных артерий у пациентов с умеренной претестовой вероятностью ишемической болезни сердца</article-title><trans-title-group xml:lang="en"><trans-title>Longitudinal Systolic Deformation and Postsystolic Shortening of The Left Ventricular Myocardium at Rest and During Stress Echocardiography as Predictors of Coronary Artery Stenosis in Patients With a Moderate Pre-Test Probability of Coronary Artery Disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8879-3791</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазур</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazur</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор; зав. кафедрой госпитальной терапии и профессиональных болезней</p></bio><bio xml:lang="en"><p>MD, Professor, Head of Chair of Hospital Therapy and Occupational Diseases</p></bio><email xlink:type="simple">mazur-tver@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4818-434X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазур</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazur</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Профессор кафедры госпитальной терапии и профессиональных болезней</p></bio><bio xml:lang="en"><p>MD, Chair of Hospital Therapy and Occupational Diseases</p></bio><email xlink:type="simple">vera.v.mazur@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1103-5001</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>Т. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>T. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p> к.м.н., доцент, зав. кафедрой пропедевтики внутренних болезней</p></bio><bio xml:lang="en"><p>PhD, Head of Chair of internal diseases</p></bio><email xlink:type="simple">tabo051310@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-6535-2744</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джанибекова</surname><given-names>Л. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhanibekova</surname><given-names>L. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., заведующая отделением неотложной кардиологии РСЦ РГБ ЛПК «КЧРКБ», доцент  кафедры внутренних болезней  Медицинского института  ФГБОУ ВО  «Северо-Кавказской государственной академии» </p></bio><bio xml:lang="en"><p>Ph.D., Chief Cardiologist of the «Karachay-Cherkess Republic», Head of the Department of Emergency Cardiology, Associate Professor of the  Department of Internal Diseases of the Medcal Institute of the North Cfucasian Academy</p></bio><email xlink:type="simple">lady.djanibekova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4719-9980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джанибекова</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhanibekova</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент  кафедры внутренних болезней, декан факультета иностранных обучающихся </p></bio><bio xml:lang="en"><p>Ph.D., Associate Professor of the Department of Internal  Medicine Dean of the Faculty of Foreign Students of the Medical Institute of the North Cfucasian Academy </p></bio><email xlink:type="simple">lady.djanibekova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9952-2447</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беганская</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Beganskaya</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент, доцент кафедры пропедевтики внутренних болезней</p></bio><bio xml:lang="en"><p>PhD, Chair of internal diseases, Tver State Medical University</p></bio><email xlink:type="simple">tabo051310@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Тверской ГМУ Минздрава России, Тверь</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tver State Medical University, Tver</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>РГБ ЛПУ «Карачаево-Черкесская республиканская клиническая больница», Черкесск;&#13;
ФГБОУ ВО «Северо-Кавказская государственная академия» Минздрава России, Черкесск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Karachay-Cherkess Republic Clinical Hospital, Cherkessk;&#13;
North Caucasian State Academy, Cherkessk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО «Северо-Кавказская государственная академия» Минздрава России, Черкесск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North Caucasian State Academy, Cherkessk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>29</day><month>08</month><year>2026</year></pub-date><volume>66</volume><issue>7</issue><fpage>56</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/3133">https://cardio.elpub.ru/jour/article/view/3133</self-uri><abstract><p>Цель    Сравнение диагностических возможностей оценки глобального продольного стрейна (ГПС), глобального постсистолического индекса (ГПСИ) и патологического постсистолического укорочения (ППСУ) в выявлении гемодинамически значимого коронарного стеноза у пациентов с умеренной претестовой вероятностью ишемической болезни сердца.</p><p>Материал и методы            В исследование включены 79 пациентов (52 мужчины, медиана возраста 62,0 года), которым были выполнены проба с физической нагрузкой на велоэргометре под эхокардиографическим контролем и инвазивная коронарография. Показатели деформации миокарда определяли до и сразу после физической нагрузки с помощью спекл-трекинг эхокардиографии.</p><p>Результаты Гемодинамически значимый коронарный стеноз выявлен у 53 пациентов. Пациенты со стенозом (1‑я группа) и без такового (2‑я группа) были сопоставимы по возрасту и половому составу, однако ППСУ в 1‑й группе чаще отмечались артериальная гипертензия (90,6% против 69,2%; р=0,0241) и сахарный диабет (32,1% против 7,7%; р=0,0236). До физической нагрузки у пациентов 1‑й группы был ниже ГПС (18,8 [16,1; 20,6] % против 21,9 [19,3; 22,8] %; р=0,0003), но выше ГПСИ (2,94 [1,69; 5,84] % против 1,62 [1,00; 2,76] %; р=0,0091) и распространенность ППСУ (50,9% против 19,2%; р=0,0073). Площадь под кривой ошибок (AUC) для ГПС как признака коронарного стеноза составляла 0,751 (95% доверительный интервал – ​ДИ 0,641–0,842), для ГПСИ – ​0,681 (95% ДИ 0,567–0,782), для ППСУ – ​0,659 (95 % ДИ 0,543–0,762). После физической нагрузки средние значения ГПС в 1‑й и 2‑й группах составили 20,3 [14,6; 24,1] и 24,3 [22,3; 27,6] % (р=0,0001) соответственно, ГПСИ – ​7,88 [4,69; 10,5] и 1,35 [0,35; 2,76] % соответственно (р&lt;0,0001), распространенность ППСУ – ​90,6 и 7,7 % соответственно (р&lt;0,0001). AUC для ГПС равнялась 0,767 (95 % ДИ 0,658–0,855), для ГПСИ – ​0,910 (95 % ДИ 0,825–0,963), для ППСУ – ​0,914 (95% ДИ 0,830–0,966).</p><p>Заключение   В покое диагностические возможности ГПС в отношении коронарного стеноза выше, чем ГПСИ и ППСУ. После физической нагрузки диагностические возможности ГПСИ и ППСУ значительно выше, чем ГПС.</p></abstract><trans-abstract xml:lang="en"><p>Aim       To compare the diagnostic performance of global longitudinal strain (GLS), the global postsystolic index (GPSI), and pathological postsystolic shortening (PSS) for detecting hemodynamically significant coronary stenosis in patients with an intermediate pre-test probability of coronary artery disease (CAD).</p><p>Material and methods             The study included 79 patients (52 men; median age: 62.0 years) who underwent bicycle stress echocardiography and invasive coronary angiography. Myocardial strain parameters were measured before and immediately post-exercise using speckle-tracking echocardiography.</p><p>Results Hemodynamically significant coronary stenosis was identified in 53 patients. Patients with stenosis (Group 1) and without stenosis (Group 2) had comparable age and sex distributions; however, hypertension (90.6% vs. 69.2%; p=0.0241) and diabetes mellitus (32.1% vs. 7.7%; p=0.0236) were significantly more prevalent in Group 1. Pre-exercise, Group 1 exhibited lower GLS (18.8% [16.1–20.6%] vs. 21.9% [19.3–22.8%]; p=0.0003), but higher GPSI (2.94% [1.69–5.84%] vs. 1.62% [1.00–2.76%]; p=0.0091) and a higher prevalence of PSS (50.9% vs. 19.2%; p=0.0073). The area under the ROC curve (AUC) for identifying coronary stenosis was 0.751 (95% confidence interval [CI]: 0.641–0.842) for GLS, 0.681 (95% CI: 0.567–0.782) for GPSI, and 0.659 (95% CI: 0.543–0.762) for PSS. Post-exercise, median values for Group 1 and Group 2 were 20.3% [14.6–24.1%] vs. 24.3% [22.3–27.6%] for GLS (p=0.0001), and 7.88% [4.69–10.5%] vs. 1.35% [0.35–2.76%] for GPSI (p&lt;0.0001). Post-exercise PSS prevalence was 90.6% vs. 7.7%, respectively (p&lt;0.0001). The AUC values were 0.767 (95% CI: 0.658–0.855) for GLS, 0.910 (95% CI: 0.825–0.963) for GPSI, and 0.914 (95% CI: 0.830–0.966) for PSS.</p><p>Conclusion       At rest, GLS demonstrates superior diagnostic performance for detecting coronary stenosis compared to GPSI and PSS. Following exercise stress, the diagnostic utility of both GPSI and PSS is significantly higher than that of GLS.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Ишемическая болезнь сердца</kwd><kwd>претестовая вероятность</kwd><kwd>стресс-эхокардиография</kwd><kwd>спекл-трекинг-эхокардиография</kwd><kwd>глобальный продольный стрейн левого желудочка</kwd><kwd>постсистолическое укорочение</kwd><kwd>постсистолический индекс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Coronary artery disease</kwd><kwd>pre-test probability</kwd><kwd>stress echocardiography</kwd><kwd>speckle-tracking echocardiography</kwd><kwd>left ventricular global longitudinal strain</kwd><kwd>post-systolic shortening</kwd><kwd>post-systolic index</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Нет внешнего финансирования.  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