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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2025.1.n2809</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-2809</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>Сравнение клинических осложнений между стимуляцией области левой ножки пучка Гиса и традиционной стимуляцией правого желудочка в долгосрочном наблюдении</article-title><trans-title-group xml:lang="en"><trans-title>Comparison of Clinical Complications Between LBBAP and Traditional RVP in Long-Term Follow-Up</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7687-4431</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чен</surname><given-names>Цзеруо</given-names></name><name name-style="western" xml:lang="en"><surname>Chen</surname><given-names>Jieruo</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD</p><p>Пекин, Китай</p></bio><bio xml:lang="en"><p>PhD</p><p>Beijing, China</p></bio><email xlink:type="simple">chenjieruo@foxmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ван</surname><given-names>Зефэн</given-names></name><name name-style="western" xml:lang="en"><surname>Wang</surname><given-names>Zefeng</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD</p><p>Пекин, Китай</p></bio><bio xml:lang="en"><p>PhD</p><p>Beijing, China</p></bio><email xlink:type="simple">wangzefeng@139.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ханг</surname><given-names>Фэй</given-names></name><name name-style="western" xml:lang="en"><surname>Hang</surname><given-names>Fei</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD</p><p>Пекин, Китай</p></bio><bio xml:lang="en"><p>PhD</p><p>Beijing, China</p></bio><email xlink:type="simple">hangfei_anzhen@163.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ву</surname><given-names>Юнцюань</given-names></name><name name-style="western" xml:lang="en"><surname>Wu</surname><given-names>Yongquan</given-names></name></name-alternatives><bio xml:lang="ru"><p>PhD</p><p>Пекин, Китай</p></bio><bio xml:lang="en"><p>PhD</p><p>Beijing, China</p></bio><email xlink:type="simple">wuyongquan67@163.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пекинская больница Аньчжэнь, Столичный медицинский университет, отделение кардиологии</institution><country>Китай</country></aff><aff xml:lang="en"><institution>Beijing Anzhen Hospital, Capital Medical University, Department of Cardiology</institution><country>China</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>31</day><month>01</month><year>2025</year></pub-date><volume>65</volume><issue>1</issue><fpage>27</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/2809">https://cardio.elpub.ru/jour/article/view/2809</self-uri><abstract><sec><title>Цель</title><p>Цель. Традиционная стимуляция правого желудочка (СПЖ) может привести к асинхронным механическим сокращениям сердца и повысить риск неблагоприятных сердечных событий. Целью данного исследования было сравнение клинических осложнений между стимуляцией области левой ножки пучка Гиса (СОЛНПГ), которая является новой и более физиологической методикой, и СПЖ в когорте, требующей желудочковой стимуляции.Материал и методы. Ретроспективное исследование было проведено на пациентах с первоначальной имплантацией двухкамерного постоянного кардиостимулятора и с долей желудочковой стимуляции более 20% с января 2019 года по декабрь 2020 года. Пациенты были разделены на группы СОЛНПГ и СПЖ с последующим проспективным наблюдением. Первичным результатом были осложнения со стороны желудочкового электрода, включая увеличение порога желудочкового электрода или снижение амплитуды зубца R. Общие осложнения были определены как осложнения желудочкового электрода, дислокация желудочкового электрода, перфорация желудочкового электрода, неблагоприятные сердечно-сосудистые события и сердечно-сосудистая смерть.Результаты. В анализ было включено в общей сложности 248 пациентов (группа СОЛНПГ, n = 98; группа СПЖ, n = 150). Длительность стимуляции QRS у пациентов с СОЛНПГ была значительно короче, чем у пациентов с СПЖ (110,3 ± 22,7 против 140,0 ± 29,3 мс, p&lt;0,01). При средней продолжительности наблюдения 13 месяцев риск осложнений со стороны желудочковых электродов был выше в группе СОЛНПГ, чем в группе СПЖ (62,0% против 36,5%, p=0,03). СОЛНПГ была сопоставима с СПЖ в течение одного года наблюдения в отношении частоты развития общих осложнений. При ультразвуковом исследовании в течение одного года наблюдения размер левого предсердия в группе СОЛНПГ был меньше, чем в группе сравнения (p=0,04). Учитывая больший начальный конечно-диастолический размер левого желудочка (КДР) в группе СОЛНПГ, сходство значений КДР в обеих группах при наблюдении предполагает, что КДР уменьшался у пациентов, получавших лечение СОЛНПГ. Не было выявлено разницы по величине фракции выброса левого желудочка (ФВ ЛЖ) (в группе СОЛНПГ, исходный уровень = 61,2 ± 8,6%) между двумя группами на исходном уровне или при наблюдении.Заключение. Пациенты с СОЛПНГ были более склонны к повышению порога желудочковых электродов и снижению амплитуды зубца R, чем пациенты с СПЖ. Риск общих осложнений при двух вариантах стимуляции был одинаковым при продолжительности наблюдения в один год. СОЛНПГ является безопасным и эффективным методом у пациентов с долей желудочковой стимуляции &gt;20% и без выраженного снижения ФВЛЖ.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background. Traditional right ventricular pacing (RVP) can lead to asynchronous cardiac mechanical contractions and increase the risk of adverse cardiac events. This study aimed to compare the clinical complications between left bundle branch area pacing (LBBAP), which is both novel and physiological, and RVP in a cohort requiring ventricular pacing.Material and methods. A retrospective study was conducted on patients with initial implantation of a dual-chamber, permanent pacemaker and with ventricular pacing proportion more than 20 % from January 2019 to December 2020. Patients were divided into the LBBAP or RVP group and follow-up was conducted routinely. The primary outcome was ventricular lead complications, including an increase in the ventricular lead threshold or a decrease in R-wave amplitude. Overall complications were defined as ventricular lead complications, ventricular lead dislocation, ventricular lead perforation, adverse cardiovascular events and cardiovascular death.Results. A total of 248 patients were included in the analysis (LBBAP, n=98; RVP, n=150). The pacing QRS duration in LBBAP patients was significantly shorter than in RVP patients (110.3±22.7 vs 140.0±29.3 ms, p&lt;0.01). For a mean follow-up duration of 13 mos, the risk of ventricular lead complications was higher in the LBBAP group than in the RVP group (62.0 % vs. 36.5 %, p=0.03). LBBAP was comparable to RVP within one year follow-up when considering overall complications. At the one year follow-up ultrasound examinations, the LA in LBBAP group was decreased (p=0.04). Considering the larger initial left ventricular end-diastolic diameter (LVEDD) in the LBBAP group, the similarity of LVEDD values in both groups at follow-up suggested that LVEDD was reduced in patients treated with LBBAP. There was no difference in left ventricular ejection fraction (LBBAP LVEF, baseline = 61.2±8.6 %) between the two groups at baseline or follow-up.Conclusions. LBBAP patients were more prone to ventricular lead threshold increase and amplitude decrease than RVP patients. The risk of overall complications in the two pacing modalities were equal in one year follow-up duration. LBBAP is safe and effective in patients with VP&gt;20 % and without seriously depressed LVEF.</p></sec><sec><title> </title><p> </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Стимуляция области левой ножки пучка Гиса</kwd><kwd>физиологическая стимуляция</kwd><kwd>брадикардия</kwd><kwd>осложнения желудочкового электрода</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Left bundle branch area pacing</kwd><kwd>physiological pacing</kwd><kwd>bradycardia</kwd><kwd>ventricular lead complications</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Конфликт интересов не заявлен</funding-statement><funding-statement xml:lang="en">No conflict of interest is reported.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Naqvi TZ, Chao C-J. 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