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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2025.4.n2746</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-2746</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>Связь между индексом массы тела и острым повреждением почек у пациентов, перенесших коронарную реваскуляризацию: ретроспективное когортное исследование на основании базы данных MIMIC-IV</article-title><trans-title-group xml:lang="en"><trans-title>Association between Body Mass Index and Acute Kidney Injury in Patients who Underwent Coronary Revascularization: A Retrospective Cohort Study from the MIMIC-IV Database</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чжан</surname><given-names>Янь</given-names></name><name name-style="western" xml:lang="en"><surname>Zhang</surname><given-names>Yan</given-names></name></name-alternatives><bio xml:lang="ru"><p>Bachelor of Science</p><p>Чжанцзякоу, Китай</p></bio><bio xml:lang="en"><p>Bachelor of Science</p><p>Zhangjiakou, China</p></bio><email xlink:type="simple">13931303478@163.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цзя</surname><given-names>Сяофэй</given-names></name><name name-style="western" xml:lang="en"><surname>Jia</surname><given-names>Xiaofei</given-names></name></name-alternatives><bio xml:lang="ru"><p>Bachelor of Science</p><p>Чжанцзякоу, Китай</p></bio><bio xml:lang="en"><p>Bachelor of Science</p><p>Zhangjiakou, China</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фань</surname><given-names>Вэньсюй</given-names></name><name name-style="western" xml:lang="en"><surname>Fan</surname><given-names>Wenxu</given-names></name></name-alternatives><bio xml:lang="ru"><p>Bachelor of Science</p><p>Чжанцзякоу, Китай</p></bio><bio xml:lang="en"><p>Bachelor of Science</p><p>Zhangjiakou, China</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гао</surname><given-names>Фэн</given-names></name><name name-style="western" xml:lang="en"><surname>Gao</surname><given-names>Feng</given-names></name></name-alternatives><bio xml:lang="ru"><p>Bachelor of Science</p><p>Чжанцзякоу, Китай</p></bio><bio xml:lang="en"><p>Bachelor of Science</p><p>Zhangjiakou, China</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цуй</surname><given-names>Хан</given-names></name><name name-style="western" xml:lang="en"><surname>Cui</surname><given-names>Hang</given-names></name></name-alternatives><bio xml:lang="ru"><p>Bachelor of Science</p><p>Чжанцзякоу, Китай</p></bio><bio xml:lang="en"><p>Bachelor of Science</p><p>Zhangjiakou, China</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первая больница Чжанцзякоу, отделение кардиохирургии</institution><country>Китай</country></aff><aff xml:lang="en"><institution>Zhangjiakou First Hospital, Department of Cardiac Surgery</institution><country>China</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>04</month><year>2025</year></pub-date><volume>65</volume><issue>4</issue><fpage>10</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/2746">https://cardio.elpub.ru/jour/article/view/2746</self-uri><abstract><p>Введение    Острое повреждение почек (ОПП) остается распространенным осложнением операции по реваскуляризации коронарных артерий и ассоциировано с повышением риска неблагоприятного исхода. Целью данного исследования была оценка связи между ИМТ и риском ОПП у пациентов, перенесших операцию по реваскуляризации коронарных артерий.Материалы и методы    В этом ретроспективном когортном исследовании использовались данные из базы данных Medical Information Mart for Intensive Care (MIMIC)-IV с 2008 по 2019 год для пациентов, перенесших операцию по реваскуляризации коронарных артерий. Конечной точкой было развитие ОПП после поступления в отделение интенсивной терапии. Ковариаты были выбраны с помощью регрессии LASSO. Однофакторные и многофакторные модели логистической регрессии были использованы для оценки связи между ИМТ и риском развития ОПП у пациентов, перенесших операцию по реваскуляризации коронарных артерий, с результатами, представленными в виде отношения шансов (OR) и 95% доверительных интервалов (CI). Анализы подгрупп были выполнены на основе возраста, характера операции, использования антикоагулянтов, а также был рассчитан балл по шкале последовательной органной недостаточности (SOFA) для дальнейшего изучения связи между ИМТ и ОПП.Результаты    В это исследование были включены 3017 пациентов, перенесших операцию по реваскуляризации коронарных артерий, из которых у 2172 (72,8%) развилось ОПП. Увеличение ИМТ было значительно связано с повышенным риском ОПП у пациентов, перенесших коронарную реваскуляризацию (OR = 1,10, 95% ДИ: 1,08–1,12), что указывает на 10% увеличение риска ОПП для каждой единицы увеличения ИМТ, скорректированное по демографическим переменным (возраст и пол) в Модели 1. После дальнейшей корректировки в Модели 2 для значимых исходных характеристик, включая сопутствующие заболевания (сахарный дибет 2 типа, сердечная недостаточность, злокачественные опухоли и хроническое заболевание почек) и системы оценки в отделении интенсивной терапии (SOFA, APS III, SAPS II, OASIS и CCI), связь оставалась статистически значимой с 11% увеличением риска ОПП на единицу увеличения ИМТ (OR = 1,11, 95% ДИ: 1,08–1,13).Заключение    ИМТ может быть перспективным параметром для оценки риска ОПП при операции реваскуляризации у пациентов, предоставляя ценную информацию для стратификации риска и ведения пациентов отделения интенсивной терапии, перенесших такие операции.</p></abstract><trans-abstract xml:lang="en"><p>Aim    Acute kidney injury (AKI) remains a common complication of coronary artery revascularization surgery and is associated with adverse outcomes in critically ill surgical patients. Body mass index (BMI) is associated with various diseases. This study aimed to evaluate the association between BMI and the risk of AKI in patients undergoing coronary artery revascularization surgery.Material and methods    In this retrospective cohort study, data were extracted from the Medical Information Mart for Intensive Care (MIMIC) – IV database from 2008 to 2019 for patients undergoing coronary artery revascularization surgery. The outcome was the occurrence of AKI after ICU admission. Covariates were selected using LASSO regression. Univariable and multivariable logistic regression models were utilized to assess the association between BMI and the odds of developing AKI in patients undergoing coronary artery revascularization surgery, with results presented as odds ratios (OR) and 95 % confidence intervals (CI). Subgroup analyses were performed based on age, surgery, anticoagulant use, and the Sequential Organ Failure Assessment (SOFA) score was computed to further explore the association between BMI and AKI.Results    This study included 3017 patients who underwent coronary artery revascularization surgery, of whom 2172 (72.8 %) developed AKI. Increasing BMI was significantly associated with elevated odds of AKI in patients undergoing coronary revascularization (OR = 1.10, 95 % CI: 1.08–1.12), indicating a 10 % increase in AKI risk for each unit increase in BMI, adjusted for demographic variables (age and gender) in Model 1. After further adjustment in Model 2 for significant baseline characteristics including comorbidities (type 2 diabetes, heart failure, malignant tumors, and chronic kidney disease) and ICU scoring systems (SOFA, APS III, SAPS II, OASIS, and CCI), the association remained significant with an 11 % increased risk of AKI per BMI unit increase (OR = 1.11, 95 % CI: 1.08–1.13).Conclusion    BMI may be a promising parameter for assessing the risk of AKI in paty revascularization surgery, providing valuable information for risk stratification and management of ICU patients undergoing such procedures.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>Острое повреждение почек</kwd><kwd>индекс массы тела</kwd><kwd>операция по реваскуляризации коронарной артерии</kwd><kwd>пациенты отделения интенсивной терапии</kwd><kwd>стратификация риска</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Acute kidney injury</kwd><kwd>body mass index</kwd><kwd>coronary artery revascularization surgery</kwd><kwd>ICU patients</kwd><kwd>risk stratification</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Конфликт интересов не заявлен</funding-statement><funding-statement xml:lang="en">No conflict of interest is reported.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ahn J, Lee YS, Lee W, Jeong B, Choi E-K, Shin DG et al. 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