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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2562</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-262</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Коморбидность и полиморбидность -современная трактовка и насущные задачи, стоящие перед терапевтическим сообществом</article-title><trans-title-group xml:lang="en"><trans-title>Comorbidity and polymorbidity -a modern interpretation and urgent tasks facing the therapeutic community</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарловская</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarlovskaya</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «ПИМУ» МЗ РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Privolzhsky Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>18</day><month>11</month><year>2018</year></pub-date><volume>58</volume><issue>9S</issue><fpage>29</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/262">https://cardio.elpub.ru/jour/article/view/262</self-uri><abstract><p>В статье представлен обзор данных, касающихся полиморбидности. Показано, что полиморбидность связана с более высокими показателями смертности, инвалидности, с побочными эффектами лечения, с повышенным использованием ресурсов системы здравоохранения, а также с более низким качеством жизни. Обсуждаются вопросы эффективного лечения людей с множественными хроническими заболеваниями. Обоснованы необходимость клинических исследований, включающих больных с множественными хроническими заболеваниями, и разработка новых клинических рекомендаций, на которые могли бы опираться практические врачи при лечении полиморбидных пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The article presents an overview of data on polymorbidity. It is shown that polymorbidity is associated with higher mortality, disability, side effects of treatment, increased use of health system resources, and also with a lower quality of life. The issues of effective treatment of people with multiple chronic diseases are discussed. The necessity of clinical trials, including patients with multiple chronic diseases, and the development of new clinical recommendations, which could be based on practical doctors in the treatment of polymorbid patients, are substantiated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>полиморбидность</kwd><kwd>коморбидность</kwd><kwd>полипрагмазия</kwd><kwd>лекарственное взаимодействие</kwd><kwd>терапевтическая конкуренция</kwd><kwd>предписание</kwd><kwd>принцип Ариадны</kwd><kwd>polymorbidity</kwd><kwd>comorbidity</kwd><kwd>polypharmacy</kwd><kwd>drug interaction</kwd><kwd>therapeutic competition</kwd><kwd>prescription</kwd><kwd>Ariadne principle</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fabbri E., Zoli M., Gonzalez-Freire M., Salive ME, Studenski SA, Ferrucci L. 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