cardioКардиологияKardiologiia0022-90402412-5660Kardiomag10.18087/cardio.2023.10.n2567cardio-2567Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИRESEARCH ARTICLESМеханическая функция и жесткость левого предсердия у пациентов с преждевременным сокращением желудочков по данным speckle tracking эхокардиографииLeft Atrial Mechanical Function And Stiffness In Patients With Premature Ventricular Contraction: A Speckle Tracking Studyhttps://orcid.org/0000-0002-2744-2891ГюнайТ.GunayT.

MD, отделение кардиологии,

Бурса

Tufan Gunay - MD,

Department of Cardiology, Bursa

drtufangunay@gmail.comhttps://orcid.org/0000-0002-0867-3264ОзтасСельви КосарOztasS. C.

MD, отделение кардиологии,

Бурса

Selvi Cosar Oztas - MD,

Department of Cardiology, Bursa

selvi35byih@hotmail.comУниверситет медицинских наук, Городская больница БурсыТурцияHealth Sciences University, Bursa City HospitalTurkey20230811202363108490Copyright © Kardiomag, 20232023KardiomagKardiomaghttps://cardio.elpub.ru/jour/about/submissions#copyrightNoticehttps://cardio.elpub.ru/jour/article/view/2567

Цель. Желудочковая экстрасистолия (ЖЭ) характеризуется преждевременной деполяризацией желудочков и ассоциирована с повышенным риском развития аритмий и структурных заболеваний сердца. Настоящее исследование было направлено на изучение связи между экстрасистолической нагрузкой и функцией левого предсердия (ЛП) у людей без известных заболеваний сердца.Материал и методы. Проведено поперечное исследование 102 пациентов с ЖЭ, обратившихся в кардиологический диспансер. Трансторакальную эхокардиографию использовали для оценки параметров левого желудочка (ЛЖ), включая массу ЛЖ, фракцию выброса ЛЖ (ФВЛЖ), глобальную продольную деформацию ЛЖ (GLS ЛЖ), а функцию ЛП оценивали с помощью визуализации деформации. Экстрасистолическая нагрузка была разделена на три группы: <10%, 10-20% и >20%.Результаты. Изменения размеров ЛЖ и индекса массы ЛЖ были выявлены в группах с нагрузкой ЖЭ 10-20% и >20%, но различия в величине ФВЛЖ и GSL ЛЖ не были статистически значимыми. Среднее значение E/e' увеличивалось по мере увеличения экстрасистолической нагрузки (р <0,001). Средняя глобальная пиковая деформация ЛП уменьшалась по мере увеличения нагрузки ЖЭ (p < 0,001), в то время как другие средние значения показателей ЛП увеличивались по мере увеличения нагрузки ЖЭ (p < 0,001). Более высокая экстрасистолическая нагрузка была связана с нарушением функции ЛП, на что указывает снижение пиковой деформации ЛП (ЖЭ <10% = 38,1±3,2; ЖЭ 10-20% = 32,4±3,2; ЖЭ >20% = 27,7±2,6, во всех группах р<0,001) и повышение его жесткости (ЖЭ <10% = 18,6±3,2; ЖЭ 10-20% = 27,5±5,5; ЖЭ >20% = 39,0±7,9, во всех группах р<0,001). Была обнаружена сильная отрицательная корреляция между глобальной пиковой деформацией ЛП и жесткостью ЛП (r = -0,779, p <0,001).Вывод. У лиц без известных заболеваний сердца более высокая нагрузка ЖЭ была связана с нарушением функции ЛП, о чем свидетельствует увеличение E/e', снижение деформации ЛП и увеличение его жесткости. Эти данные свидетельствуют о том, что высокая частота желудочковой экстрасистолии может способствовать дисфункции ЛП, потенциально увеличивая риск сердечно-сосудистых событий.

Aim. Ventricular extrasystole (PVC) is characterized by premature ventricular depolarization and is associated with increased risk of arrhythmias and structural heart disease. This study aimed to investigate the association between the PVC burden and left atrial (LA) function in individuals without known cardiac disease.Material and methods. A cross-sectional study was conducted on 102 patients with PVCs who were admitted to a cardiology clinic. Transthoracic echocardiography was used to assess left ventricle (LV) parameters, including LV mass, LV ejection fraction (LVEF), LV global longitudinal strain (LVGLS), and LA function was evaluated using strain imaging. The PVC burden was categorized into three groups: <10 %, 10–20 %, and >20 %.Results. Changes in LV dimensions and LV mass index were associated with the groups with the PVC burden with 10–20 %, and >20 %. but differences in LVEF and LVGSL were not significant. Mean E / e’ increased as the PVC burden increased (p<0.001). The mean global LA peak strain decreased as the PVC burden increased (p<0.001), while other mean LA measurements increased as the PVC burden increased (p<0.001) A higher PVC burden was associated with impaired LA function, as indicated by decreased global LA peak strain (PVC burden <10 %=38.1±3.2 vs. PVC burden 10–20 %=32.4±3.2 vs. PVC burden >20 %=27.7±2.6, in all groups p<0.001) and with increased LA stiffness (PVC burden <10 %=18.6±3.2 vs. PVC burden 10–20 %=27.5±5.5 vs. PVC burden >20 %=39.0±7.9, in all groups p<0.001). A strong negative correlation was found between global LA peak strain and LA stiffness (r=–0.779, p<0.001).Conclusion. In individuals without known cardiac disease, a higher PVC burden was associated with impaired LA function, indicated by increased E / e’, decreased LA strain, and increased LA stiffness. These findings suggest that PVC burden may contribute to LA dysfunction, potentially increasing the risk of cardiovascular events.

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The authors declare that there are no conflicts of interest present.