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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2023.9.n2292</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-2292</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>Время «дверь-баллон» при инфаркте миокарда без подъема сегмента ST может быть пересмотрено в соответствии с индексом системного иммунного воспаления</article-title><trans-title-group xml:lang="en"><trans-title>Door to Balloon Time of Non-ST Elevation Myocardial Infarction May be Reconsidered According to Systemic Immune-Inflammation Index</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озгейик</surname><given-names>Мехмет</given-names></name><name name-style="western" xml:lang="en"><surname>Ozgeyik</surname><given-names>Mehmet</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент , MD, г.н.с.</p><p>Эскишехир, Турция</p></bio><bio xml:lang="en"><p>Associate Professor, MD, Chief Researcher</p><p>Department of Cardiology, Eskisehir, Turkey</p></bio><email xlink:type="simple">mehmetozgeyik@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Йылдырым</surname><given-names>Озге Тургай</given-names></name><name name-style="western" xml:lang="en"><surname>Yildirim</surname><given-names>Ozge Turgay</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент, MD</p><p>Эскишехир, Турция</p></bio><bio xml:lang="en"><p>Associate Professor, MD, Asistant Researcher</p><p>Department of Cardiology, Eskisehir, Turkey</p></bio><email xlink:type="simple">ozgeturgay@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озгейик</surname><given-names>Муфиде Окай</given-names></name><name name-style="western" xml:lang="en"><surname>Ozgeyik</surname><given-names>Mufide Okay</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент, MD</p><p>Эскишехир, Турция</p></bio><bio xml:lang="en"><p>Associate Professor, MD, Asistant Researcher</p><p>Department of Hematology, Eskisehir, Turkey</p></bio><email xlink:type="simple">mufide_okay@yahoo.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурат</surname><given-names>Бектас</given-names></name><name name-style="western" xml:lang="en"><surname>Murat</surname><given-names>Bektas</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент, MD</p><p>Эскишехир, Турция</p></bio><bio xml:lang="en"><p>Associate Professor, MD, Asistant Researcher</p><p>Department of Cardiology, Eskisehir, Turkey</p></bio><email xlink:type="simple">dr.bektash@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурат</surname><given-names>Селда</given-names></name><name name-style="western" xml:lang="en"><surname>Murat</surname><given-names>Selda</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент, MD</p><p>Эскишехир, Турция</p></bio><bio xml:lang="en"><p>Associate Professor, MD, Senior Researcher</p><p>Deparment of Cardiology, Eskisehir, Turkey</p></bio><email xlink:type="simple">selda.eraslan@hotmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская больница Эскишехира, отделение кардиологии</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Eskisehir City Hospital</institution><country>Turkey</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская больница Эскишехира, отделение гематологии</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Eskisehir City Hospital</institution><country>Turkey</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Университет Османгази, кафедра кардиологии</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Osmangazi University</institution><country>Turkey</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2023</year></pub-date><volume>63</volume><issue>9</issue><fpage>56</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/2292">https://cardio.elpub.ru/jour/article/view/2292</self-uri><abstract><p>Цель    Ранняя диагностика и лечение очень важны при остром коронарном синдроме (ОКС). Предыдущие исследования показали, что не всех пациентов с инфарктом миокарда без подъема сегмента ST (ИМбпST) следует рассматривать и лечить одинаково. Индекс системного иммунного воспаления (SII), который является легкодоступным, быстро вычисляемым и экономически эффективным параметром, оценивался в этом исследовании для определения оптимального времени вмешательства при ИМбпST.Материал и методы    В исследование были включены 469 пациентов с диагнозом ОКС. Пациентов с ИМ с подъемом сегмента ST (ИМпST) и ИМбпST сравнивали по величине SII. Был проведен одномерный и бинарный логистический регрессионный анализ, чтобы определить, какие параметры оказывают существенное влияние на различение типов инфаркта миокарда.Результаты    Средний возраст пациентов составил 61,43±11,52 года, 348 (74,2%) были мужчинами. У пациентов с ИМбпST с показателем SII выше 768x109/л могут быть отнесены к группе ИМпST (p&lt;0,001). Однофакторный анализ и бинарная логистическая регрессия показали, что только SII и артериальная гипертензия оказывали статистически значимое влияние на дифференциацию ИМпST и ИМбпST. Кроме того, значение SII, равное 1105 x 109/л было точкой отсечения для определения сердечно-сосудистой выживаемости (p&lt;0,001, AUC=0,741). Это исследование было проведено, чтобы выяснить, каких пациентов с ИМбпST следует лечить чрескожно сразу после первого медицинского контакта в соответствии с SII. Было установлено, что значение SII выше 768 x 109/л позволяет отнести пациента к группе ИМпST.Заключение    В заключение, пациенты с ИМбпST со значением SII выше 768x109/л могут рассматриваться как ИМпST, и должны получить лечение через 120 минут после первого контакта. Кроме того, было обнаружено, что SII является предиктором смертности от сердечно-сосудистых заболеваний после инфаркта миокарда, что может быть использовано для выявления пациентов с высоким риском после чрескожного коронарного вмешательства.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>Aim    Early diagnosis and treatment is very important in acute coronary syndromes (ACS). Previous studies showed that not all non-ST elevation myocardial infarction (NSTEMI) patients should be considered and treated in the same way. The systemic immune-inflammation index (SII), which is an easily accessible, rapidly computed, and cost-effective parameter, was evaluated in this study to determine the optimal intervention time for NSTEMI.Material and methods    469 patients diagnosed with ACS were included to the study. STEMI and NSTEMI patients were compared according to their SII. Univariate and binary logistic regression analysis were performed to determine which parameters have a significant effect on the discrimination of types of myocardial infarction.Results    The mean age of the patients was 61.43±11.52 yrs, and 348 (74.2 %) were male. NSTEMI patients with an SII value higher than 768×109 / l may be assumed to be STEMI (p&lt;0.001). Univariate analysis and binary logistic regression showed that only SII and hypertension had statistically impact on differentiation of STEMI and NSTEMI. In addition, SII value of 1105×109 / l was the cut-off point for discrimination of cardiovascular survival (p&lt;0.001, AUC =0.741). This study was performed to find out which NSTEMI patients should be treated percutaneously immediately after first medical contact according to SII. It was found that, SII value of higher than 768×109 / l is related with STEMI.Conclusion    In conclusion, NSTEMI patients with a SII value higher than 768×109 / l may be considered as STEMI and treated with in 120 min after first contact. In addition, SII was found to be a cardiovascular mortality predictor after myocardial infarction, and this may be used for identifying high-risk patients after percutaneous coronary intervention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Острый коронарный синдром</kwd><kwd>инфаркт миокарда с подъемом сегмента ST</kwd><kwd>индекс системного иммунного воспаления</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Acute coronary syndrome</kwd><kwd>ST elevation myocardial infarction</kwd><kwd>systemic immune-inflammation index</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Конфликт интересов не заявлен</funding-statement><funding-statement xml:lang="en">No conflict of interest is reported.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Naghavi M, Abajobir AA, Abbafati C, Abbas KM, Abd-Allah F, Abera SF et al. 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