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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2024.3.n2253</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-2253</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESEARCH ARTICLES</subject></subj-group></article-categories><title-group><article-title>Возможности диагностики ишемической дисфункции левого желудочка с помощью значений деформации, показателей вращения у больных инфарктом миокарда различной локализации</article-title><trans-title-group xml:lang="en"><trans-title>Limitations of Diagnosis of Ischemic Left Ventricular Dysfunction Using the Values of Strain, Twist and Untwist in Patients With Myocardial Infarction of Various Localization</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1551-9767</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Швец</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shvets</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач-кардиолог отделения кардиологии 2 и врач ультразвуковой диагностики, к.м.н.</p><p> </p></bio><bio xml:lang="en"><p>Сardiologist and ultrasound diagnostics </p></bio><email xlink:type="simple">denpost-card@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1302-9326</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поветкин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Povetkin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор зав. кафедрой клинической фармакологии </p><p> </p></bio><bio xml:lang="en"><p>PhD, university professor, head of  Department of clinical Pharmacology </p></bio><email xlink:type="simple">clinfarm@kursknet.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>БУЗ Орловской области «Орловская областная клиническая больница», Орел</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Orlov Region Clinical Hospital, Orel</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России, Курск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk State Medical University, Kursk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>31</day><month>03</month><year>2024</year></pub-date><volume>64</volume><issue>3</issue><fpage>55</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/2253">https://cardio.elpub.ru/jour/article/view/2253</self-uri><abstract><sec><title>Цель</title><p>Цель. Сравнение возможности диагностики регионарной и глобальной дисфункции миокарда с помощью величины продольной, циркулярной деформации, скручивания и раскручивания левого желудочка (ЛЖ) у больных инфарктом миокарда (ИМ) различной локализации.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Включенных в исследование пациентов (n=121) распределили на 3 группы: больные с нестабильной стенокардией (n=30), больные с передним ИМ (n=45), больные с нижним ИМ (n=46). Проведены клинико-лабораторное и инструментальное исследования, в том числе эхокардиография. При количественном анализе сократимости ЛЖ измерены максимальные систолические пики регионарной и глобальной продольной, циркулярной деформации, систолической и диастолической ротации, скручивания и раскручивания ЛЖ.</p></sec><sec><title>Результаты</title><p>Результаты. Выявлено, что для переднего ИМ характерно поражение верхушечных сегментов ЛЖ, для нижнего ИМ – базальных. При переднем ИМ выявлено снижение продольной деформации менее 14,5 % и циркулярной деформации менее 19,3 % в апикальном сегменте переднеперегородочной стенки (ППС) ЛЖ. При акинезии апикального сегмента ППС ЛЖ продольная и циркулярная деформация снижаются до менее 10 %. Величина циркулярной деформации верхушечного сегмента ППС ЛЖ: порог диагностики 19,3 %, чувствительность (Se) 87 %, специфичность (Sp) 90 % – превосходит таковую продольной деформации в качестве диагностики регионарной ишемической дисфункции при переднем ИМ. Величина циркулярной деформации базального сегмента нижней стенки ЛЖ при нижнем ИМ имеет большее диагностическое значение для выявления регионарной систолической дисфункции по сравнению со значением продольной деформации данного сегмента ЛЖ. Порог диагностики составил 17,3 %, Se 79 %, Sp 80 %.</p></sec><sec><title>Заключение</title><p>Заключение. Снижение циркулярной деформации ППС ЛЖ менее 19,3 % в апикальном сегменте ЛЖ более специфично (Sp 90 %) для диагностики регионарной систолической дисфункции при переднем ИМ, чем снижение продольной деформации. Величина циркулярной деформации менее 17,3 % в базальном сегменте нижней стенки ЛЖ более специфична (Sp 80 %) по сравнению с продольной деформацией данного сегмента для диагностики регионарной систолической дисфункции при нижнем ИМ. Преимущественное поражение верхушки ЛЖ при переднем ИМ может приводить к систолической и диастолической дисфункции миокарда, что проявляется снижением циркулярной деформации, скручивания и раскручивания ЛЖ.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To compare capabilities for diagnosing regional and global myocardial dysfunction using the values of longitudinal and circular strain, left ventricular (LV) torsion and untwisting in patients with myocardial infarction (MI) of various locations.</p></sec><sec><title>Material and methods</title><p>Material and methods. Patients included in the study (n=121) were divided into three groups: patients with unstable angina (n=30), patients with anterior MI (n=45), and patients with inferior MI (n=46). Clinical, laboratory and instrumental test were performed, including echocardiography. For a quantitative analysis of LV contractility, the maximum systolic peaks of regional and global longitudinal and circular strain, systolic and diastolic rotation, LV torsion and untwisting were measured.</p></sec><sec><title>Results</title><p>Results. Anterior MI was characterized by injury of the LV apical segments, while inferior MI was characterized by injury of the basal segments. In anterior MI, the longitudinal strain was reduced less than 14.5% and circular strain less than 19.3% in the apical segment of the LV anteroseptal wall (ASW). In akinesia of the LV ASW apical segment, longitudinal and circular strains were reduced less than 10%. The magnitude of the circular strain of the LV ASW apical segment (diagnostic threshold 19.3%, sensitivity (Se) 87%, specificity (Sp) 90%) was superior to that of the longitudinal strain as a diagnostic marker for regional ischemic dysfunction in anterior MI. The magnitude of the circular strain of the basal segment of the LV inferior wall in inferior MI has a greater diagnostic value for identifying regional systolic dysfunction than the value of the longitudinal strain of this LV segment. The diagnostic threshold was 17.3%, Se 79%, Sp 80%.</p></sec><sec><title>Conclusion</title><p>Conclusion. A decrease in the circular strain of the LV ASW less than 19.3% in the LV apical segment is more specific (Sp 90%) for diagnosing regional systolic dysfunction in anterior MI than a decrease in longitudinal strain. A circular strain value of less than 17.3% in the basal segment of the LV inferior wall is more specific (Sp 80%) than the longitudinal strain of this segment for diagnosing regional systolic dysfunction in inferior MI. Predominant injury to the LV apex in anterior MI can cause systolic and diastolic myocardial dysfunction, which is manifested by a decrease in LV circular deformation, torsion and untwisting.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>Деформация</kwd><kwd>скручивание</kwd><kwd>раскручивание левого желудочка</kwd><kwd>инфаркт миокарда</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Strain</kwd><kwd>torsion</kwd><kwd>left ventricular untwisting</kwd><kwd>myocardial infarction</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Источников финансирования не было.  Конфликт интересов не заявлен.</funding-statement><funding-statement xml:lang="en">No funding was received for this study.  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