<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2017.10021</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-22</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИЧЕСКАЯ КАРДИОЛОГИЯ ПРИЛОЖЕНИЕ ДЛЯ ПРАКТИЧЕСКИХ ВРАЧЕЙ КЛИНИЧЕСКИЕ СЕМИНАРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICAL CARDIOLOGY SUPPLEMENT FOR PRACTISING PHYSICIANS CLINICAL SEMINARS</subject></subj-group></article-categories><title-group><article-title>Актуальные вопросы подбора антикоагулянтной терапии для длительной профилактики тромбоэмболических осложнений</article-title><trans-title-group xml:lang="en"><trans-title>Actual Issues of Choosing Anticoagulant Therapy for Long-term Prophylaxis of Thromboembolic Complications</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlova</surname><given-names>Tatyana V.</given-names></name></name-alternatives><email xlink:type="simple">ptvsam63@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воронова</surname><given-names>И. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Voronova</surname><given-names>I. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дупляков</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Duplyakov</surname><given-names>D. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет»; ГБУЗ «Самарский областной клинический кардиологический диспансер» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University; Samara Regional Cardiology Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>17</day><month>11</month><year>2018</year></pub-date><volume>57</volume><issue>8</issue><fpage>71</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/22">https://cardio.elpub.ru/jour/article/view/22</self-uri><abstract><p>В статье представлены актуальные проблемы подбора антикоагулянтной терапии для длительной профилактики тромбоэмболических осложнений у амбулаторного пациента с фибрилляцией предсердий, хронической сердечной недостаточностью и хронической болезнью почек.</p></abstract><trans-abstract xml:lang="en"><p>The article contains presentation of actual problems of selection of anticoagulant therapy for long term prevention of thromboembolic complications in outpatients with atrial fibrillation, chronic heart failure, and chronic kidney disease.tions in ambulatory Patients with atrial fibrillation, chronic heart failure and chronic kidney disease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>хроническая сердечная недостаточность</kwd><kwd>хроническая болезнь почек</kwd><kwd>антикоагулянтная терапия</kwd><kwd>atrial fibrillation</kwd><kwd>chronic heart failure</kwd><kwd>chronic kidney disease</kwd><kwd>anticoagulant therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chugh S.S., Havmoeller R., Narayanan K. et al. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation 2014;129:837-847.</mixed-citation><mixed-citation xml:lang="en">Chugh S.S., Havmoeller R., Narayanan K. et al. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation 2014;129:837-847.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Dzau V., Braunwald E. Resolved and unresolved issues in the prevention and treatment of coronary artery disease: a workshop consensus statement. Am Heart J. 1991;121(4 Pt 1):1244-1263.</mixed-citation><mixed-citation xml:lang="en">Dzau V., Braunwald E. Resolved and unresolved issues in the prevention and treatment of coronary artery disease: a workshop consensus statement. Am Heart J. 1991;121(4 Pt 1):1244-1263.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Olesen J.B., Lip G.Y., Kamper A.L. Stroke and bleeding in atrial fibrillation with chronic kidney disease. N. Engl J. Med 2012;367(7):625-635.</mixed-citation><mixed-citation xml:lang="en">Olesen J.B., Lip G.Y., Kamper A.L. Stroke and bleeding in atrial fibrillation with chronic kidney disease. N. Engl J. Med 2012;367(7):625-635.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Benjamin E.J., Levy D., Vaziri S.M. et al. Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. JAMA 1994;271(11):840-844.</mixed-citation><mixed-citation xml:lang="en">Benjamin E.J., Levy D., Vaziri S.M. et al. Independent risk factors for atrial fibrillation in a population-based cohort. The Framingham Heart Study. JAMA 1994;271(11):840-844.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Cleland J.G., Chattopadhyay S., Khand A. et al. Prevalence and incidence of arrhythmias and sudden death in heart failure. Heart Fail Rev 2002;7(3):229-242.</mixed-citation><mixed-citation xml:lang="en">Cleland J.G., Chattopadhyay S., Khand A. et al. Prevalence and incidence of arrhythmias and sudden death in heart failure. Heart Fail Rev 2002;7(3):229-242.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Bos M.J., Koudstaal P.J., Hofman A., Breteler M.M. Decreased glomerular filtration rate is a risk factor for hemorrhagic but not for ischemic stroke: the Rotterdam Study. Stroke 2007;38:3127-3132.</mixed-citation><mixed-citation xml:lang="en">Bos M.J., Koudstaal P.J., Hofman A., Breteler M.M. Decreased glomerular filtration rate is a risk factor for hemorrhagic but not for ischemic stroke: the Rotterdam Study. Stroke 2007;38:3127-3132.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Sarnak M.J., Levey A.S., Schoolwerth A.C. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension 2003;42:1050-1065.</mixed-citation><mixed-citation xml:lang="en">Sarnak M.J., Levey A.S., Schoolwerth A.C. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension 2003;42:1050-1065.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Watanabe H., Watanabe T., Sasaki S. Close bidirectional relationship between chronic kidney disease and atrial fibrillation: the Niigata preventive medicine study. Am Heart J. 2009;158(4):629-636.</mixed-citation><mixed-citation xml:lang="en">Watanabe H., Watanabe T., Sasaki S. Close bidirectional relationship between chronic kidney disease and atrial fibrillation: the Niigata preventive medicine study. Am Heart J. 2009;158(4):629-636.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Zimmerman D., Sood M.M., Rigatto C. et al. Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysis. Nephrol Dial Transplant 2012;27:3816-3822.</mixed-citation><mixed-citation xml:lang="en">Zimmerman D., Sood M.M., Rigatto C. et al. Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysis. Nephrol Dial Transplant 2012;27:3816-3822.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ronco C., McCullough P., Anker S. Cardio-renal syndromes: report from the consensus conference of the Acute Dialysis Quality Initiative. Eur Heart J. 2010;31:703-711.</mixed-citation><mixed-citation xml:lang="en">Ronco C., McCullough P., Anker S. Cardio-renal syndromes: report from the consensus conference of the Acute Dialysis Quality Initiative. Eur Heart J. 2010;31:703-711.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Iguchi Y., Kimura K., Kobayashi K. Relation of atrial fibrillation to glomerular filtration rate. AmJ Cardiol 2008;102(8):1056-1059.</mixed-citation><mixed-citation xml:lang="en">Iguchi Y., Kimura K., Kobayashi K. Relation of atrial fibrillation to glomerular filtration rate. AmJ Cardiol 2008;102(8):1056-1059.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Go A.S., Fang M.C., Udaltsova N. et al.; ATRIA Study Investigators. Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. Circulation 2009;119:1363-1369.</mixed-citation><mixed-citation xml:lang="en">Go A.S., Fang M.C., Udaltsova N. et al.; ATRIA Study Investigators. Impact of proteinuria and glomerular filtration rate on risk of thromboembolism in atrial fibrillation: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. Circulation 2009;119:1363-1369.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Olesen J.B., Lip G.Y., Kamper A.L. Stroke and bleeding in atrial fibrillation with chronic kidney disease. N. EnglJ Med 2012;367(7): 625-635.</mixed-citation><mixed-citation xml:lang="en">Olesen J.B., Lip G.Y., Kamper A.L. Stroke and bleeding in atrial fibrillation with chronic kidney disease. N. EnglJ Med 2012;367(7): 625-635.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">ESC Guidelines. Management of atrial fibrillation. Eur Heart J. 2016;37(38):2893-2962.</mixed-citation><mixed-citation xml:lang="en">ESC Guidelines. Management of atrial fibrillation. Eur Heart J. 2016;37(38):2893-2962.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Терещенко С. Н., Романова Н. В., Жиров И. В. и др. Российский регистр больных хронической сердечной недостаточностью и фибрилляцией предсердий (РИФ-ХСН): клинико-демографические харак теристики выборки на момент включения в регистр. Журнал Сердечная недостаточность 2016;17 (6):418-426</mixed-citation><mixed-citation xml:lang="en">Терещенко С. Н., Романова Н. В., Жиров И. В. и др. Российский регистр больных хронической сердечной недостаточностью и фибрилляцией предсердий (РИФ-ХСН): клинико-демографические харак теристики выборки на момент включения в регистр. Журнал Сердечная недостаточность 2016;17 (6):418-426</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hart R.G., Pearce L.A., Aguilar M.I. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007;146:857-867.</mixed-citation><mixed-citation xml:lang="en">Hart R.G., Pearce L.A., Aguilar M.I. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007;146:857-867.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Cherian T.S., Shrader P., Fonarow G.C. et al. Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality-of-Life Scores in Patients With Heart Failure (from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF]). Am J. Cardiol 2017;119(11):1763-1769.</mixed-citation><mixed-citation xml:lang="en">Cherian T.S., Shrader P., Fonarow G.C. et al. Effect of Atrial Fibrillation on Mortality, Stroke Risk, and Quality-of-Life Scores in Patients With Heart Failure (from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation [ORBIT-AF]). Am J. Cardiol 2017;119(11):1763-1769.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Beyer-Westendorf J., Forster K., Pannach S. et al. Rates, management, and outcome of rivaroxaban bleeding in daily care: Results from the Dresden NOAC registry. Blood 2014;124(6):955-962.</mixed-citation><mixed-citation xml:lang="en">Beyer-Westendorf J., Forster K., Pannach S. et al. Rates, management, and outcome of rivaroxaban bleeding in daily care: Results from the Dresden NOAC registry. Blood 2014;124(6):955-962.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Michalski F., Tittl L., Werth S. et al. Selection, management, and outcome of vitamin K. antagonist-treated patients with atrial fibrillation not switched to novel oral anticoagulants. Results from the Dresden NOAC registry. Thromb Haemost 2015;114(5):1076-1084.</mixed-citation><mixed-citation xml:lang="en">Michalski F., Tittl L., Werth S. et al. Selection, management, and outcome of vitamin K. antagonist-treated patients with atrial fibrillation not switched to novel oral anticoagulants. Results from the Dresden NOAC registry. Thromb Haemost 2015;114(5):1076-1084.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Coleman C.I., Roberts M.S., Sobieraj D.M. et al. Curr Med Res Opin 2012;28(5):669-680.</mixed-citation><mixed-citation xml:lang="en">Coleman C.I., Roberts M.S., Sobieraj D.M. et al. Curr Med Res Opin 2012;28(5):669-680.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">van Diepen S., Hellkamp A.S., Patel M.R. Efficacy and safety of rivaroxaban in patients with heart failure and nonvalvular atrial fibrillation: insights from ROCKET AF. Circ Heart Fail 2013;6(4):740-747.</mixed-citation><mixed-citation xml:lang="en">van Diepen S., Hellkamp A.S., Patel M.R. Efficacy and safety of rivaroxaban in patients with heart failure and nonvalvular atrial fibrillation: insights from ROCKET AF. Circ Heart Fail 2013;6(4):740-747.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Fox K.A., Piccini J.P., Wojdyla D. et al. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment. Eur Heart J 2011;32(19):2387-2394.</mixed-citation><mixed-citation xml:lang="en">Fox K.A., Piccini J.P., Wojdyla D. et al. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment. Eur Heart J 2011;32(19):2387-2394.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Fordyce C.B., Hellkamp A.S., Lokhnygina Y. et al. On-Treatment Outcomes in Patie3 4nts With Worsening Renal Function With Rivaroxaban Compared With Warfarin: Insights From ROCKET AF. Circulation 2016;134(1):37-47.</mixed-citation><mixed-citation xml:lang="en">Fordyce C.B., Hellkamp A.S., Lokhnygina Y. et al. On-Treatment Outcomes in Patie3 4nts With Worsening Renal Function With Rivaroxaban Compared With Warfarin: Insights From ROCKET AF. Circulation 2016;134(1):37-47.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Hijazi Z., Hohnloser S.H., Andersson U. et al. Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time. Insights From the ARISTOTLE Randomized Clinical Trial JAMA Cardiol 2016;1(4):451-460.</mixed-citation><mixed-citation xml:lang="en">Hijazi Z., Hohnloser S.H., Andersson U. et al. Efficacy and Safety of Apixaban Compared With Warfarin in Patients With Atrial Fibrillation in Relation to Renal Function Over Time. Insights From the ARISTOTLE Randomized Clinical Trial JAMA Cardiol 2016;1(4):451-460.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">McHorney C.A. et al., Rivaroxaban users have significantly less treatment discontinuation compared with users of other oral anticoagulants in non-valvular atrial fibrillation. American College of Cardiology Conference 2017, Washington, DC, USA, 17-19 March 2017; Poster 1252-1306.</mixed-citation><mixed-citation xml:lang="en">McHorney C.A. et al., Rivaroxaban users have significantly less treatment discontinuation compared with users of other oral anticoagulants in non-valvular atrial fibrillation. American College of Cardiology Conference 2017, Washington, DC, USA, 17-19 March 2017; Poster 1252-1306.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Andrade J.G., Krahn A.D., Skanes A.C. et al. Values and Preferences of Physicians and Patients With Nonvalvular Atrial Fibrillation Who Receive Oral Anticoagulation Therapy for Stroke Prevention. Can J Cardiol 2016;32(6):747-753.</mixed-citation><mixed-citation xml:lang="en">Andrade J.G., Krahn A.D., Skanes A.C. et al. Values and Preferences of Physicians and Patients With Nonvalvular Atrial Fibrillation Who Receive Oral Anticoagulation Therapy for Stroke Prevention. Can J Cardiol 2016;32(6):747-753.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Beyer-Westendorf J., Forster K., Ebertz F. et al. Drug persistence with rivaroxaban therapy in atrial fibrillation patients-results from the Dresden non-interventional oral anticoagulation registry. Europace 2015;17(4):530-538.</mixed-citation><mixed-citation xml:lang="en">Beyer-Westendorf J., Forster K., Ebertz F. et al. Drug persistence with rivaroxaban therapy in atrial fibrillation patients-results from the Dresden non-interventional oral anticoagulation registry. Europace 2015;17(4):530-538.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">McHorney C.A., Peterson E.D., Laliberte F. et al. Comparison of Adherence to Rivaroxaban Versus Apixaban Among Patients With Atrial Fibrillation. Clin Ther 2016;38(11):2477-2488.</mixed-citation><mixed-citation xml:lang="en">McHorney C.A., Peterson E.D., Laliberte F. et al. Comparison of Adherence to Rivaroxaban Versus Apixaban Among Patients With Atrial Fibrillation. Clin Ther 2016;38(11):2477-2488.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
