cardioКардиологияKardiologiia0022-90402412-5660Kardiomag10.18087/cardio.2022.3.n2010cardio-2010Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИRESEARCH ARTICLESВзаимосвязь степени ночного снижения артериального давления и выраженности атеросклероза коронарных артерий у больных гипертонической болезньюAssociation of dipping pattern of blood pressure and atherosclerotic burden of coronary arteries in hypertensive patientshttps://orcid.org/0000-0002-6307-5136ТасбулакО.TaşbulakO.

MD, Кафедра кардиологии

Стамбул

Omer Tasbulak, MD, Department of Cardiology

Istanbul

omertasbulak@hotmail.comhttps://orcid.org/0000-0002-5578-432XАктемурТ.AktemurT.

MD, Кафедра кардиологии

Стамбул

tugbaktemur@gmail.comШахинА. А.ŞahinA. A.

MD, Кафедра кардиологии

Стамбул

Ahmet Anıl Şahin, MD, Department of Cardiology

Istanbul 

aanilsahin@hotmail.comДемирА. Р.DemirA. R.

MD, Кафедра кардиологии

Стамбул

Ali Riza Demir, MD, Department of Cardiology

Istanbul

alirdemir1986@gmail.comГюлерА.GülerA.

MD, Кафедра кардиологии

Стамбул

 

Arda Guler, MD, Department of Cardiology

Istanbul

drardaguler@gmail.comТопелД.TopelC.

MD, Кафедра радиологии

Стамбул

 

Cagdas Topel, MD, Department of Radiology

Istanbul

CGDSTPL@gmail.comТуркватанА.TurkvatanA.

MD, Кафедра радиологии

Стамбул

Aysel Turkvatan, MD, Department of Radiology

Istanbul

aturkvatan@yahoo.comПусуроглуХ.PusurogluH.

профессор, Кафедра кардиологии

Стамбул

 

Hamdi Pusuroglu, Prof. DR, Department of Cardiology

Istanbul

hpusts@gmail.comЭртюркМ.ErturkM.

профессор, Кафедра кардиологии

Стамбул

 

Mehmet Erturk, Prof.Dr, Department of Cardiology

Istanbul

drerturk@gmail.comУниверситет наук о здоровье, Учебно-исследовательский госпиталь торакальной и сердечно-сосудистой хирургии им. Мехмета Акифа ЭрсояТурцияUniversity of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research HospitalTurkeyУниверситет Истинье, медицинский факультет, Лив Хоспитал БахчешехирТурцияIstinye University, Faculty of Medicine, Liv Hospital BahcesehirTurkeyУниверситет медицинских наук Башакшехир Джам и городская больница СакураТурцияUniversity of Health Sciences Basaksehir Cam and Sakura City HospitalTurkey2022310320226235664Copyright © Kardiomag, 20222022KardiomagKardiomaghttps://cardio.elpub.ru/jour/about/submissions#copyrightNoticehttps://cardio.elpub.ru/jour/article/view/2010

Цель    Целью данного исследования было определить связь между характером ночного снижения АД и ишемической болезнью сердца у пациентов с артериальной гипертензией.Материал и методы    В исследование было включено 356 больных АГ. Ретроспективно оценивались результаты амбулаторного мониторирования АД, эхокардиографии и коронарной компьютерной томографической ангиографии. На основании данных амбулаторного мониторирования АД пациенты были разделены на две группы: 1) больные с достаточным снижением ночного АД (ДП); 2) пациенты с недостаточным снижением ночного АД (НДП).Результаты    Среди 356 пациентов 145 были мужчинами (40,7%). Статус курения был выше у больных с НДП (р=0,023). Использование статинов у пациентов с нормальной динамикой АД было выше, чем у пациентов с НДП (p = 0,027). Существенных различий в эхокардиографических данных не было. У 58,6% пациентов без наличия атеросклеротических бляшек наблюдалось снижение ночного АД (p<0,05), однако у 84,4% пациентов с наличием атеросклеротических бляшек, занимающих >50% просвета сосуда, было недостаточное снижение ночного АД (p<0,001).Вывод    Недостаточное снижение ночного АД может быть связано с усилением атеросклеротического процесса в коронарных артериях, а пациенты с НДП могут иметь повышенную атеросклеротическую нагрузку на коронарные артерии по сравнению с пациентами со снижением ночного АД.

 

Aim    The aim of this study was to determine the association between the dipping pattern of BP and coronary artery disease in hypertensive patients.Material and methods    A total of 356 hypertensive patients were included in the study. The results of ambulatory BP monitoring, echocardiography, and coronary computerised tomographic angiography were evaluated retrospectively. The patients were divided into two groups on the basis of their ambulatory BP monitoring: 1) patients with the dipping pattern of BP; 2) patients with the non-dipping pattern (NDP).Results    Among the 356 patients, 145 were male (40.7 %). The smoking status was higher in patients with NDP (p=0.023). The statin usage in patients with the dipping pattern was higher in patients with NDP (p=0.027). There were no significant differences in the echocardiographic findings. 58.6 % of the patients without plaque formation had the dipping pattern of BP (p<0.05), however 84.4 % of patients with >50 % plaque formation had the NDP of BP (p<0.001).Conclusion    The NDP of BP might be related to the increased atherosclerotic process in coronary arteries, and pa­tients with NDP might have an increased atherosclerotic burden for coronary arteries when compared with patients with a dipping pattern.

 

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The authors declare that there are no conflicts of interest present.