<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cardio</journal-id><journal-title-group><journal-title xml:lang="ru">Кардиология</journal-title><trans-title-group xml:lang="en"><trans-title>Kardiologiia</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0022-9040</issn><issn pub-type="epub">2412-5660</issn><publisher><publisher-name>Kardiomag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18087/cardio.2017.7.10000</article-id><article-id custom-type="elpub" pub-id-type="custom">cardio-2</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEADING ARTICLE</subject></subj-group></article-categories><title-group><article-title>Перфузия миокарда: что понимается под этим термином при визуализации различными методами лучевой диагностики?</article-title><trans-title-group xml:lang="en"><trans-title>Myocardial Perfusion Imaging Modalities: What do we Really see?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аншелес</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ansheles</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергиенко</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergienko</surname><given-names>V. B.</given-names></name></name-alternatives><email xlink:type="simple">a.ansheles@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Российский кардиологический научно-производственный комплекс» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Cardiology Research and Production Complex</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>17</day><month>11</month><year>2018</year></pub-date><volume>57</volume><issue>7</issue><fpage>5</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kardiomag, 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Kardiomag</copyright-holder><copyright-holder xml:lang="en">Kardiomag</copyright-holder><license xlink:href="https://cardio.elpub.ru/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://cardio.elpub.ru/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://cardio.elpub.ru/jour/article/view/2">https://cardio.elpub.ru/jour/article/view/2</self-uri><abstract><p>Оценка перфузии, тяжести ишемии и объема жизнеспособного миокарда, в том числе радионуклидными методами однофотонной или позитронной эмиссионной томографии, является одним из важнейших этапов обследования пациентов с ишемической болезнью сердца. Однако в последние годы отмечается тенденция добавлять «перфузионную» приставку и к другим методам кардиологической лучевой диагностики (эхокардиографии, компьютерной и магнитно-резонансной томографии). Такая терминологическая неопределенность приводит к ошибочной оценке кардиологом реальных возможностей данных методов. В обзоре уточнены определения терминов «перфузия», «ишемия» и «жизнеспособность» миокарда. Сравнение возможностей лучевых методов проведено с позиции соответствия кинетики используемых индикаторов и фактически визуализируемых процессов в миокарде.</p></abstract><trans-abstract xml:lang="en"><p>Assessment of perfusion, severity of ischemia and the volume of viable myocardium, including single-photon or positron emission tomography (SPECT and PET ) is one of the most important stages of examination of patients with ischemic heart disease. However, in recent years “perfusion” prefix was added to other cardiologic modalities (echocardiography, magnetic resonance and computed tomography). Such a terminological uncertainty leads cardiologists to an erroneous evaluation of real possibilities of these methods. The review clarifies the definitions of terms “perfusion”, “ischemia”, and “viability” of the myocardium. Imaging modalities are compared from the perspective of compliance with the kinetics of the indicators used and actually visualized myocardial processes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>радиология</kwd><kwd>миокард</kwd><kwd>перфузия</kwd><kwd>жизнеспособность</kwd><kwd>radiology</kwd><kwd>myocardium</kwd><kwd>perfusion</kwd><kwd>viability</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Montalescot G., Sechtem U., Achenbach S. et al. 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 2013;34(38):2949-3003.</mixed-citation><mixed-citation xml:lang="en">Montalescot G., Sechtem U., Achenbach S. et al. 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 2013;34(38):2949-3003.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Le Bihan D., Turner R. The capillary network: a link between IVIM and classical perfusion. Magn Reson Med 1992;27(l):171-178.</mixed-citation><mixed-citation xml:lang="en">Le Bihan D., Turner R. The capillary network: a link between IVIM and classical perfusion. Magn Reson Med 1992;27(l):171-178.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Schmitt F., Stehling M.K., Turner R. Echo-Planar Imaging: Theory, Technique and Application. Springer, 1998.</mixed-citation><mixed-citation xml:lang="en">Schmitt F., Stehling M.K., Turner R. Echo-Planar Imaging: Theory, Technique and Application. Springer, 1998.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Schneider M. Characteristics of SonoVuetrade mark. Echocardiography 1999;16(7, Pt 2):743-746.</mixed-citation><mixed-citation xml:lang="en">Schneider M. Characteristics of SonoVuetrade mark. Echocardiography 1999;16(7, Pt 2):743-746.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Saeed M., Hetts S.W., Jablonowski R., Wilson M.W. Magnetic resonance imaging and multi-detector computed tomography assessment of extracellular compartment in ischemic and non-ischemic myocardial pathologies. World J Cardiol 2014;6(11):1192-1208.</mixed-citation><mixed-citation xml:lang="en">Saeed M., Hetts S.W., Jablonowski R., Wilson M.W. Magnetic resonance imaging and multi-detector computed tomography assessment of extracellular compartment in ischemic and non-ischemic myocardial pathologies. World J Cardiol 2014;6(11):1192-1208.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">McKillop J.H. Thallium 201 scintigraphy. West J Med 1980;133(1):26-43.</mixed-citation><mixed-citation xml:lang="en">McKillop J.H. Thallium 201 scintigraphy. West J Med 1980;133(1):26-43.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Boden W. E., O'Rourke R. A., Teo K. K. et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 2007;356(15):1503-1516.</mixed-citation><mixed-citation xml:lang="en">Boden W. E., O'Rourke R. A., Teo K. K. et al. Optimal medical therapy with or without PCI for stable coronary disease. N Engl J Med 2007;356(15):1503-1516.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hachamovitch R., Hayes S.W., Friedman J.D. et al. Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography. Circulation 2003;107(23):2900-2907.</mixed-citation><mixed-citation xml:lang="en">Hachamovitch R., Hayes S.W., Friedman J.D. et al. Comparison of the short-term survival benefit associated with revascularization compared with medical therapy in patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography. Circulation 2003;107(23):2900-2907.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hachamovitch R., Di Carli M.F. Methods and limitations of assessing new noninvasive tests: Part II: Outcomes-based validation and reliability assessment of noninvasive testing. Circulation 2008;117(21):2793-2801.</mixed-citation><mixed-citation xml:lang="en">Hachamovitch R., Di Carli M.F. Methods and limitations of assessing new noninvasive tests: Part II: Outcomes-based validation and reliability assessment of noninvasive testing. Circulation 2008;117(21):2793-2801.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Tonino P. A., De Bruyne B., Pijls N. H. et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 2009;360(3):213-224.</mixed-citation><mixed-citation xml:lang="en">Tonino P. A., De Bruyne B., Pijls N. H. et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 2009;360(3):213-224.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Majmudar M.D., Nahrendorf M. Cardiovascular molecular imaging: the road ahead. J Nucl Med 2012;53(5):673-676.</mixed-citation><mixed-citation xml:lang="en">Majmudar M.D., Nahrendorf M. Cardiovascular molecular imaging: the road ahead. J Nucl Med 2012;53(5):673-676.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sato A., Hiroe M., Tamura M. et al. Quantitative measures of coronary stenosis severity by 64-Slice CT angiography and relation to physiologic significance of perfusion in nonobese patients: comparison with stress myocardial perfusion imaging. J Nucl Med 2008;49(4):564-572.</mixed-citation><mixed-citation xml:lang="en">Sato A., Hiroe M., Tamura M. et al. Quantitative measures of coronary stenosis severity by 64-Slice CT angiography and relation to physiologic significance of perfusion in nonobese patients: comparison with stress myocardial perfusion imaging. J Nucl Med 2008;49(4):564-572.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">van Nunen L. X., Zimmermann F. M., Tonino P. A. et al. Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial. Lancet 2015;386(10006):1853-1860.</mixed-citation><mixed-citation xml:lang="en">van Nunen L. X., Zimmermann F. M., Tonino P. A. et al. Fractional flow reserve versus angiography for guidance of PCI in patients with multivessel coronary artery disease (FAME): 5-year follow-up of a randomised controlled trial. Lancet 2015;386(10006):1853-1860.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Johnson N. P., Gould K. L. Fractional Flow Reserve Returns to Its Origins: Quantitative Cardiac Positron Emission Tomography. Circ Cardiovasc Imaging 2016;9(9).</mixed-citation><mixed-citation xml:lang="en">Johnson N. P., Gould K. L. Fractional Flow Reserve Returns to Its Origins: Quantitative Cardiac Positron Emission Tomography. Circ Cardiovasc Imaging 2016;9(9).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Windecker S., Kolh P., Alfonso F. et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J 2014;35(37):2541-2619.</mixed-citation><mixed-citation xml:lang="en">Windecker S., Kolh P., Alfonso F. et al. 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J 2014;35(37):2541-2619.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gibbons R.J., Hodge D.O., Berman D.S. et al. Long-term outcome of patients with intermediate-risk exercise electrocardiograms who do not have myocardial perfusion defects on radionuclide imaging. Circulation 1999;100(21):2140-2145.</mixed-citation><mixed-citation xml:lang="en">Gibbons R.J., Hodge D.O., Berman D.S. et al. Long-term outcome of patients with intermediate-risk exercise electrocardiograms who do not have myocardial perfusion defects on radionuclide imaging. Circulation 1999;100(21):2140-2145.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bonow R.O., Maurer G., Lee K.L. et al. Myocardial viability and survival in ischemic left ventricular dysfunction. N Engl J Med 2011;364(17):1617-1625.</mixed-citation><mixed-citation xml:lang="en">Bonow R.O., Maurer G., Lee K.L. et al. Myocardial viability and survival in ischemic left ventricular dysfunction. N Engl J Med 2011;364(17):1617-1625.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Гуля М.О., Лишманов Ю.Б., Завадовский К.В., Лебедев Д.И. Состояние метаболизма жирных кислот в миокарде левого желудочка и прогноз эффективности кардиоресинхронизирующей терапии у пациентов с дилатационной кардиомиопатией. Российский кардиологический журнал 2014;113(9):61-67)</mixed-citation><mixed-citation xml:lang="en">Гуля М.О., Лишманов Ю.Б., Завадовский К.В., Лебедев Д.И. Состояние метаболизма жирных кислот в миокарде левого желудочка и прогноз эффективности кардиоресинхронизирующей терапии у пациентов с дилатационной кардиомиопатией. Российский кардиологический журнал 2014;113(9):61-67)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Ghosh N., Rimoldi O.E., Beanlands R.S., Camici P.G. Assessment of myocardial ischaemia and viability: role of positron emission tomography. Eur Heart J 2010;31(24):2984-2995</mixed-citation><mixed-citation xml:lang="en">Ghosh N., Rimoldi O.E., Beanlands R.S., Camici P.G. Assessment of myocardial ischaemia and viability: role of positron emission tomography. Eur Heart J 2010;31(24):2984-2995</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Лишманов Ю.Б., Ефимова И.Ю., Чернов В.И. и др. Сцинтиграфия как инструмент диагностики, прогнозирования и мониторинга лечения болезней сердца. Сибирский медицинский журнал 2007;22(3):74-77)</mixed-citation><mixed-citation xml:lang="en">Лишманов Ю.Б., Ефимова И.Ю., Чернов В.И. и др. Сцинтиграфия как инструмент диагностики, прогнозирования и мониторинга лечения болезней сердца. Сибирский медицинский журнал 2007;22(3):74-77)</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Сергиенко В.Б., Аншелес А.А. Томографические методы в оценке перфузии миокарда. Вестник рентгенологии и радиологии 2010;3:10-14</mixed-citation><mixed-citation xml:lang="en">Сергиенко В.Б., Аншелес А.А. Томографические методы в оценке перфузии миокарда. Вестник рентгенологии и радиологии 2010;3:10-14</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Shrestha U., Sciammarella M., Alhassen F. et al. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. J Nucl Cardiol 2017; 24(1):268-277</mixed-citation><mixed-citation xml:lang="en">Shrestha U., Sciammarella M., Alhassen F. et al. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. J Nucl Cardiol 2017; 24(1):268-277</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Мочула А.В., Завадовский К.В., Лишманов Ю.Б. Методика определения резерва миокардиального кровотока с использованием нагрузочной динамической однофотонной эмиссионной компьютерной томографии. Бюллетень экспериментальной биологии и медицины 2015;160(12):845-848</mixed-citation><mixed-citation xml:lang="en">Мочула А.В., Завадовский К.В., Лишманов Ю.Б. Методика определения резерва миокардиального кровотока с использованием нагрузочной динамической однофотонной эмиссионной компьютерной томографии. Бюллетень экспериментальной биологии и медицины 2015;160(12):845-848</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Husmann L., Herzog B.A., Gaemperli O., et al. Diagnostic accuracy of computed tomography coronary angiography and evaluation of stress-only single-photon emission computed tomography/ computed tomography hybrid imaging: comparison of prospective electrocardiogram-triggering vs. retrospective gating. Eur Heart J 2009;30(5):600-607.</mixed-citation><mixed-citation xml:lang="en">Husmann L., Herzog B.A., Gaemperli O., et al. Diagnostic accuracy of computed tomography coronary angiography and evaluation of stress-only single-photon emission computed tomography/ computed tomography hybrid imaging: comparison of prospective electrocardiogram-triggering vs. retrospective gating. Eur Heart J 2009;30(5):600-607.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Florian A., Jurcut R., Ginghina C., Bogaert J. Cardiac magnetic resonance imaging in ischemic heart disease: a clinical review. J Med Life 2011;4(4):330-345.</mixed-citation><mixed-citation xml:lang="en">Florian A., Jurcut R., Ginghina C., Bogaert J. Cardiac magnetic resonance imaging in ischemic heart disease: a clinical review. J Med Life 2011;4(4):330-345.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hulten E., Ahmadi A., Blankstein R. CT Assessment of Myocardial Perfusion and Fractional Flow Reserve. Prog Cardiovasc Dis 2015;57(6):623-631.</mixed-citation><mixed-citation xml:lang="en">Hulten E., Ahmadi A., Blankstein R. CT Assessment of Myocardial Perfusion and Fractional Flow Reserve. Prog Cardiovasc Dis 2015;57(6):623-631.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Lee J.H., Han D., Danad I. et al. Multimodality Imaging in Coronary Artery Disease: Focus on Computed Tomography. J Cardiovasc Ultrasound 2016;24(1):7-17.</mixed-citation><mixed-citation xml:lang="en">Lee J.H., Han D., Danad I. et al. Multimodality Imaging in Coronary Artery Disease: Focus on Computed Tomography. J Cardiovasc Ultrasound 2016;24(1):7-17.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Bamberg F., Marcus R.P., Becker A. et al. Dynamic myocardial CT perfusion imaging for evaluation of myocardial ischemia as determined by MR imaging. JACC Cardiovasc Imaging 2014;7(3):267-277.</mixed-citation><mixed-citation xml:lang="en">Bamberg F., Marcus R.P., Becker A. et al. Dynamic myocardial CT perfusion imaging for evaluation of myocardial ischemia as determined by MR imaging. JACC Cardiovasc Imaging 2014;7(3):267-277.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Pesenti-Rossi D., Peyrou J., Baron N., et al. Cardiac MRI: technology, clinical applications, and future directions. Ann Cardiol Angeiol (Paris) 2013;62(5):326-341.</mixed-citation><mixed-citation xml:lang="en">Pesenti-Rossi D., Peyrou J., Baron N., et al. Cardiac MRI: technology, clinical applications, and future directions. Ann Cardiol Angeiol (Paris) 2013;62(5):326-341.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Аншелес А.А., Шульгин Д.Н., Соломяный В.В., Сергиенко В.Б. Сопоставление результатов нагрузочных проб, данных однофотонной эмиссионной компьютерной томографии миокарда и коронарографии у больных ишемической болезнью сердца. Кардиологический вестник 2012;2:10-17</mixed-citation><mixed-citation xml:lang="en">Аншелес А.А., Шульгин Д.Н., Соломяный В.В., Сергиенко В.Б. Сопоставление результатов нагрузочных проб, данных однофотонной эмиссионной компьютерной томографии миокарда и коронарографии у больных ишемической болезнью сердца. Кардиологический вестник 2012;2:10-17</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Аншелес А.А., Шульгин Д.Н., Соломяный В.В., Сергиенко В.Б. Сопоставление результатов нагрузочных проб, данных однофотонной эмиссионной компьютерной томографии миокарда и коронарографии у больных ишемической болезнью сердца. Кардиологический вестник 2012;2:10-17</mixed-citation><mixed-citation xml:lang="en">Аншелес А.А., Шульгин Д.Н., Соломяный В.В., Сергиенко В.Б. Сопоставление результатов нагрузочных проб, данных однофотонной эмиссионной компьютерной томографии миокарда и коронарографии у больных ишемической болезнью сердца. Кардиологический вестник 2012;2:10-17</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Сергиенко В. Б., Саютина Е. В., Самойленко Л. Е. и др. Роль дисфункции эндотелия в развитии ишемии миокарда у больных ишемической болезнью сердца с неизмененными и малоизмененными коронарными артериями. Кардиология 1999;39(1):25-30</mixed-citation><mixed-citation xml:lang="en">Сергиенко В. Б., Саютина Е. В., Самойленко Л. Е. и др. Роль дисфункции эндотелия в развитии ишемии миокарда у больных ишемической болезнью сердца с неизмененными и малоизмененными коронарными артериями. Кардиология 1999;39(1):25-30</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
