cardioКардиологияKardiologiia0022-90402412-5660Kardiomag10.18087/cardio.2021.4.n1408cardio-1408Research ArticleОБЗОРЫREVIEWSПоражения сердца у больных COVID-19Cardiac Involvement in COVID-19https://orcid.org/0000-0002-8255-4159СугралиевА. Б.SugraliyevA. B.

Кафедра внутренних болезней с курсом пропедевтики, зав. кафедрой

head of department

Asugraliyev@gmail.comКазахский Национальный медицинский университет им С.Д Асфендиярова, Алматы, КазахстанКазахстанKazakh National Medical University, Almaty, KazakhstanKazakhstan2021040520216141523Copyright © Kardiomag, 20212021KardiomagKardiomaghttps://cardio.elpub.ru/jour/about/submissions#copyrightNoticehttps://cardio.elpub.ru/jour/article/view/1408

Новая коронавирусная инфекция COVID-19 – высококонтагиозное вирусное заболевание с развитием острого тяжелого респираторного синдрома, в основе которого лежит развитие выраженного тромбовоспалительного синдрома. По мере увеличения количества больных COVID-19 появились публикации относительно поражения сердца, особенно у пациентов с тяжелыми и критическими формами заболевания. В настоящем обзоре описываются роль рецептора ангиотензинпревращающего фермента 2‑го типа в регуляции внедрения вируса, разнообразие поражения сердца, коронарных артерий, а также значение артериальной гипертензии и применение блокаторов ренин-ангиотензин-альдостероновой системы в прогнозе больных COVID-19.

The novel coronavirus infection, COVID-19, is a highly contagious viral disease associated with acute, severe respiratory syndrome, which is based on the development of pronounced thrombo-inflammatory syndrome. As the number of patients with COVID-19 increased, heart damage has been reported, especially in patients with severe and critical COVID-19. This review describes the role of angiotensin-converting enzyme 2 receptor in the regulation of viral entry, the variety of damages to the heart and coronary arteries, and the importance of arterial hypertension and of the use of renin-angiotensin-aldosterone system inhibitors in the prognosis of patients with COVID-19.

Новая коронавирусная инфекция COVID-19острое повреждение сердцамиокардиткоронарные тромбозысердечная недостаточностьNovel coronavirus infection COVID-19acute heart injurymyocarditiscoronary thrombosesheart failureКонфликт интересов не заявлен.No conflict of interest is reported.ReferencesShi S, Qin M, Shen B, Cai Y, Liu T, Yang F et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiology. 2020;5(7):802–10. DOI: 10.1001/jamacardio.2020.0950Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiology. 2020;5(7):802–10. DOI: 10.1001/jamacardio.2020.0950Cui J, Li F, Shi Z-L. Origin and evolution of pathogenic coronaviruses. Nature Reviews Microbiology. 2019;17(3):181–92. DOI: 10.1038/s41579-018-0118-9Cui J, Li F, Shi Z-L. Origin and evolution of pathogenic coronaviruses. Nature Reviews Microbiology. 2019;17(3):181–92. 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The authors declare that there are no conflicts of interest present.